Add to ORKGBackground: Elevated homocysteine concentrations, a likely risk factor for cardiovascular disease, can be lowered effectively with folic acid. The minimum dose of folic acid required for maximal reduction of homocysteine concentrations is not yet known reliably. Objective: We aimed to determine the lowest folic acid dose that decreases plasma homocysteine concentrations adequately in healthy older adults. Design: A dose-response trial with a randomized, double-blind, parallel-group, placebo-controlled design was carried out among 316 Dutch men and women aged 50–75 y. Subjects received daily for 12 wk either a placebo or 1 of the 6 following folic acid doses
Background: Folic acid fortification has resulted in a dramatic increase in folate intake in the Uni...
OBJECTIVES We sought to study the effect of low-dose folic acid supplementation or optimization o...
Background & Aims: At least 500 μg of folic acid are required daily to treat hyperhomocysteinem...
Background: Elevated homocysteine concentrations, a likely risk factor for cardiovascular disease, c...
The authors' objective in this study was to estimate the changes in serum folate and homocysteine co...
OBJECTIVE: The aim of our randomized, controlled trial was to verify the effect of folic acid supple...
Plasma homocysteine, which is increased after menopause, can be a risk factor for cardiovascular dis...
Elevated plasma homocysteine concentrations are associated with an increased risk of cardiovascular ...
Elevated homocysteine levels are associated with an increased cardiovascular disease (CVD) risk, but...
Objective: In 2009, Australia implemented mandatory folic acid fortification in wheat flour for brea...
folic acid is expected to reduce mortality from ischemic heart disease. Homocysteine reduction is kn...
BACKGROUND: Dietary supplementation with B vitamins that lower blood homocysteine concentrations is ...
Objective: To determine the size of reduction in homocysteine concentrations produced by dietary sup...
Background: Observational studies have shown that low folate and elevated homocysteine concentration...
The objective of this study was to determine the size of reduction in homocysteine concentrations pr...
Background: Folic acid fortification has resulted in a dramatic increase in folate intake in the Uni...
OBJECTIVES We sought to study the effect of low-dose folic acid supplementation or optimization o...
Background & Aims: At least 500 μg of folic acid are required daily to treat hyperhomocysteinem...
Background: Elevated homocysteine concentrations, a likely risk factor for cardiovascular disease, c...
The authors' objective in this study was to estimate the changes in serum folate and homocysteine co...
OBJECTIVE: The aim of our randomized, controlled trial was to verify the effect of folic acid supple...
Plasma homocysteine, which is increased after menopause, can be a risk factor for cardiovascular dis...
Elevated plasma homocysteine concentrations are associated with an increased risk of cardiovascular ...
Elevated homocysteine levels are associated with an increased cardiovascular disease (CVD) risk, but...
Objective: In 2009, Australia implemented mandatory folic acid fortification in wheat flour for brea...
folic acid is expected to reduce mortality from ischemic heart disease. Homocysteine reduction is kn...
BACKGROUND: Dietary supplementation with B vitamins that lower blood homocysteine concentrations is ...
Objective: To determine the size of reduction in homocysteine concentrations produced by dietary sup...
Background: Observational studies have shown that low folate and elevated homocysteine concentration...
The objective of this study was to determine the size of reduction in homocysteine concentrations pr...
Background: Folic acid fortification has resulted in a dramatic increase in folate intake in the Uni...
OBJECTIVES We sought to study the effect of low-dose folic acid supplementation or optimization o...
Background & Aims: At least 500 μg of folic acid are required daily to treat hyperhomocysteinem...