and Event-Related Potentials in Schizophrenia

Clinical experiences indicate that schizophrenic cognitive disturbances may be partly due to the unsuccess-ful construction of their cognitive context. In this article, two experi-ments are introduced in which schizophrenic deficits in utilization of information for construction of effec-tive cognitive context were examined through measurements of event-related potentials, particularly P300s. In a 3-tone discrimination task, schizophrenic subjects failed to elicit P300s to frequent nontarget tone