Add to ORKGSparfloxacin was found to display a biphask response against Escherichia coli, Staphylococcus aureus and Staphylococcus epidermidis in nutrient broth. Its optimum bactericidal concentration was found to be identical for all three species which contrasts with other clinically available fluoroquinolones that are more active against E. coli than against staphylococci. Bacterial protein and RNA synthesis as well as cell division were not found to be essential for all the lethality of spar-floxacin, which hence displays bactericidal mechanism B. However, sparfloxacin was unable to kill bacteria in absence of oxygen
The activity of the fluoroquinolone olamufloxacin (HSR-903) against Legionella spp. was studied in v...
ObjectiveTo investigate the in vitro potency and spectrum of activity of gatifloxacin and five compa...
Background : Levofloxacin(LVFX), an optical isomer of ofloxacin (OFLX), was reported to be approxima...
E-4904, were compared with that of ciprofloxacin and sparfloxacin against 1106 clinical isolates. Ag...
The in-vitro activity of Bay y 3118, a new quinolone antimicrobial was compared with that of ciprofl...
Sparfloxacin is a new antimicrobial that, while maintaining a good activity against gram negative ba...
The in vitro activities of three new quinolones (sparfloxacin, CI-960, and PD 131,628) were compared...
In vitro activities of LB20304a were compared with those of grepafloxacin (OPC-17116), Q-35, ciprofl...
The pharmacokinetics of ciprofloxacin and sparfloxacin were simulated in vitro and the effects of ph...
tetracycline, cephalothin, penicillin G, and amoxicillin-clavulanic acid against 173 recent clinical...
The increasing emergence of penicillin-resistant and multiresistant strains of Streptococcus pneumon...
We investigated the effect of sparfloxacin, a new broad-spectrum fluoroquinolone, on the morphology,...
Sparfloxacin, a difluorquinolone derivative, is a potent antibacterial agent active against a wide r...
The prophylactic and therapeutic activities of three broad-spectrum fluoroquinolones were evaluated ...
The in vitro antibacterial activity of DU-6859a, a new fluoroquinolone, against a wide variety of cl...
The activity of the fluoroquinolone olamufloxacin (HSR-903) against Legionella spp. was studied in v...
ObjectiveTo investigate the in vitro potency and spectrum of activity of gatifloxacin and five compa...
Background : Levofloxacin(LVFX), an optical isomer of ofloxacin (OFLX), was reported to be approxima...
E-4904, were compared with that of ciprofloxacin and sparfloxacin against 1106 clinical isolates. Ag...
The in-vitro activity of Bay y 3118, a new quinolone antimicrobial was compared with that of ciprofl...
Sparfloxacin is a new antimicrobial that, while maintaining a good activity against gram negative ba...
The in vitro activities of three new quinolones (sparfloxacin, CI-960, and PD 131,628) were compared...
In vitro activities of LB20304a were compared with those of grepafloxacin (OPC-17116), Q-35, ciprofl...
The pharmacokinetics of ciprofloxacin and sparfloxacin were simulated in vitro and the effects of ph...
tetracycline, cephalothin, penicillin G, and amoxicillin-clavulanic acid against 173 recent clinical...
The increasing emergence of penicillin-resistant and multiresistant strains of Streptococcus pneumon...
We investigated the effect of sparfloxacin, a new broad-spectrum fluoroquinolone, on the morphology,...
Sparfloxacin, a difluorquinolone derivative, is a potent antibacterial agent active against a wide r...
The prophylactic and therapeutic activities of three broad-spectrum fluoroquinolones were evaluated ...
The in vitro antibacterial activity of DU-6859a, a new fluoroquinolone, against a wide variety of cl...
The activity of the fluoroquinolone olamufloxacin (HSR-903) against Legionella spp. was studied in v...
ObjectiveTo investigate the in vitro potency and spectrum of activity of gatifloxacin and five compa...
Background : Levofloxacin(LVFX), an optical isomer of ofloxacin (OFLX), was reported to be approxima...