Tuberculosis (TB) is a leading cause worldwide of human mortality attributable to a single infectious agent. Recent studies tar-geting candidate genes and “case-control ” association have revealed numerous polymorphisms implicated in host susceptibility to TB. Here, we review current progress in the understanding of causative polymorphisms in host innate immune genes associ-ated with TB pathogenesis. We discuss genes encoding several types of proteins: macrophage receptors, such as the mannose receptor (MR, CD206), dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN, CD209), Dectin-1, Toll-like receptors (TLRs), complement receptor 3 (CR3, CD11b/CD18), nucleotide oligomerization domain 1 (NOD1) and NOD2, CD14, P2X7
<p>Tuberculosis (TB) is a multifactorial disease governed by bacterial, host and environmental facto...
Introduction: Susceptibility to tuberculosis (TB) infection varies in individuals and is linked to g...
The different manifestations of infection with Mycobacterium tuberculosis reflect the balance betwee...
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (M.tb), remains a lead...
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a major health problem, with 10 mi...
Background and Objective: Tuberculosis (TB), the leading cause of morbidity and mortality by a singl...
Tuberculosis (TB) caused by the human pathogen Mycobacterium tuberculosis, is the leading cause of m...
Tuberculosis (TB) is the leading cause of death worldwide due to an infectious agent. Data have accu...
Although host genetics influences susceptibility to tuberculosis (TB), few genes determining disease...
Although host genetics influences susceptibility to tuberculosis (TB), few genes determining disease...
Although host genetics influences susceptibility to tuberculosis (TB), few genes determining disease...
Despite high rates of exposure, only 5-10% of people infected with Mycobacterium tuberculosis will d...
Objectives: The association of toll-like receptors (TLRs) and matrix metalloproteinases (MMPs) singl...
<p>Tuberculosis (TB) is a multifactorial disease governed by bacterial, host and environmental facto...
<p>Tuberculosis (TB) is a multifactorial disease governed by bacterial, host and environmental facto...
<p>Tuberculosis (TB) is a multifactorial disease governed by bacterial, host and environmental facto...
Introduction: Susceptibility to tuberculosis (TB) infection varies in individuals and is linked to g...
The different manifestations of infection with Mycobacterium tuberculosis reflect the balance betwee...
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (M.tb), remains a lead...
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a major health problem, with 10 mi...
Background and Objective: Tuberculosis (TB), the leading cause of morbidity and mortality by a singl...
Tuberculosis (TB) caused by the human pathogen Mycobacterium tuberculosis, is the leading cause of m...
Tuberculosis (TB) is the leading cause of death worldwide due to an infectious agent. Data have accu...
Although host genetics influences susceptibility to tuberculosis (TB), few genes determining disease...
Although host genetics influences susceptibility to tuberculosis (TB), few genes determining disease...
Although host genetics influences susceptibility to tuberculosis (TB), few genes determining disease...
Despite high rates of exposure, only 5-10% of people infected with Mycobacterium tuberculosis will d...
Objectives: The association of toll-like receptors (TLRs) and matrix metalloproteinases (MMPs) singl...
<p>Tuberculosis (TB) is a multifactorial disease governed by bacterial, host and environmental facto...
<p>Tuberculosis (TB) is a multifactorial disease governed by bacterial, host and environmental facto...
<p>Tuberculosis (TB) is a multifactorial disease governed by bacterial, host and environmental facto...
Introduction: Susceptibility to tuberculosis (TB) infection varies in individuals and is linked to g...
The different manifestations of infection with Mycobacterium tuberculosis reflect the balance betwee...