Add to ORKGA Disintegrin And Metalloprotease (ADAM) family members expressed in male reproductive tissues are divided phylogenet-ically into three major groups. In the present study, we analyzed six ADAMs in one of the groups (ADAMs 4, 6, 24, 26, 29, and 30) of which function is largely unknown. Our results showed that most of the ADAMs undergo unique processing during sperm maturation and are located at the surface of sperm head. We found that the levels of ADAM4 and ADAM6 are dramatically reduced in Adam2 and Adam3 knockout sperm defective in various fertilization processes. We observed premature processing of ADAM4 in the Adam3-null mice. Furthermore, we obtained a result showing complex formation of ADAM6 with ADAM2 and ADAM3 in testis. Taken toge...
Since the discovery of the first disintegrin protein from snake venom and the following identificati...
-15,-17, and ADAMTS-1 proteins might play a role in mouse uterus during periimplantation period was ...
Peptide mimetics from the predicted binding sites in the disintegrin domains of the five testis-expr...
Background As a group of membrane-anchored proteins, the proteins containing a disintegrin and metal...
Fertilization represents the culmination of a series of complex interactions between male and female...
The ADAMs (a disintegrin and metalloproteinase) are a fascinating family of transmembrane and secret...
BACKGROUND: Extracellular metolloproteases have been implied in different process such as cell death...
ADAMs (A Disintegrin And Metalloprotease) are membrane-bound enzymes, capable of shedding a multitud...
AbstractFertilin α and β, previously known as PH-30 α and β, are two subunits of a guinea pig sperm ...
The ‘A-disintegrin and metalloproteinase ’ (ADAM) and ‘A-disintegrin and metalloproteinase with thro...
Abstract Background The metalloprotease-disintegrin family, or ADAM, proteins, are implicated in cel...
Cleavage of proteins inserted into the plasma membrane (shedding) is an essential process controllin...
<div><p>Members of the disintegrin metalloproteinase (ADAM) family have important functions in regul...
ADAM metalloprotease-disintegrins share a common modular structure of functional domains for proteo...
The sperm surface protein fertilin is a heterodimer composed of $\alpha$ and $\beta$ subunits that a...
Since the discovery of the first disintegrin protein from snake venom and the following identificati...
-15,-17, and ADAMTS-1 proteins might play a role in mouse uterus during periimplantation period was ...
Peptide mimetics from the predicted binding sites in the disintegrin domains of the five testis-expr...
Background As a group of membrane-anchored proteins, the proteins containing a disintegrin and metal...
Fertilization represents the culmination of a series of complex interactions between male and female...
The ADAMs (a disintegrin and metalloproteinase) are a fascinating family of transmembrane and secret...
BACKGROUND: Extracellular metolloproteases have been implied in different process such as cell death...
ADAMs (A Disintegrin And Metalloprotease) are membrane-bound enzymes, capable of shedding a multitud...
AbstractFertilin α and β, previously known as PH-30 α and β, are two subunits of a guinea pig sperm ...
The ‘A-disintegrin and metalloproteinase ’ (ADAM) and ‘A-disintegrin and metalloproteinase with thro...
Abstract Background The metalloprotease-disintegrin family, or ADAM, proteins, are implicated in cel...
Cleavage of proteins inserted into the plasma membrane (shedding) is an essential process controllin...
<div><p>Members of the disintegrin metalloproteinase (ADAM) family have important functions in regul...
ADAM metalloprotease-disintegrins share a common modular structure of functional domains for proteo...
The sperm surface protein fertilin is a heterodimer composed of $\alpha$ and $\beta$ subunits that a...
Since the discovery of the first disintegrin protein from snake venom and the following identificati...
-15,-17, and ADAMTS-1 proteins might play a role in mouse uterus during periimplantation period was ...
Peptide mimetics from the predicted binding sites in the disintegrin domains of the five testis-expr...