Breaks in sedentary time: beneficial associations with metabolic risk

OBJECTIVE — Total sedentary (absence of whole-body movement) time is associated with obesity, abnormal glucose metabolism, and the metabolic syndrome. In addition to the effects of total sedentary time, themanner in which it is accumulatedmay also be important.We examined the association of breaks in objectively measured sedentary time with biological markers of metabolic risk. RESEARCHDESIGNANDMETHODS — Participants (n 168, mean age 53.4 years) for this cross-sectional study were recruited from the 2004–2005 Australian Diabetes, Obesity and Lifestyle study. Sedentary timewasmeasured by an accelerometer (counts/minute1 100) worn during waking hours for seven consecutive days. Each interruption in sedentary time (counts/min100) was considered a break. Fasting plasma glucose, 2-h plasma glucose, serum triglycerides, HDL cholesterol, weight, height, waist circumference, and resting blood pressure were measured. MatLab was used to derive the breaks variable; SPSS was used for the statistical analysis. RESULTS — Independent of total sedentary time and moderate-to-vigorous intensity activity time, increased breaks in sedentary time were beneficially associated with waist circumferenc