Ten patients with cystic fibrosis received 19 therapeutic courses of ciprofloxacin at a dose of 750 mg orally twice daily. The length of therapy ranged from two to five weeks except for one patient who was treated for six weeks. The mean peak serum concentration of ciprofloxacin was 3·41 mg/I and the mean trough level was 1·11 mg!1. For comparison nine patients were treated with the combination of azlocillin at a dose of 350 mg/kg/day in four divided doses and tobramycin at an initial dose of 9 mg/kg/day in three divided doses. All patients were infected with Pseudomonas aeruginosa except for one patient in whom P. cepacia grew in the sputum cultures; the MICs of ciprofloxacin ranged from 0·05 to 1·56 mg/I. The results obtained with these t...
AbstractChronic respiratory infection caused by Pseudomonas aeruginosa is the main driver of morbidi...
Twelve courses of intravenous temocillin were given in combination with an intravenous aminoglycosid...
Abstract Chronic Pseudomonas aeruginosa lung infection in cystic fibrosis (CF) patients is caused by...
The clinical efficacy and safety of ciprofloxacin and ofloxacin were compared in a prospective, rand...
Pseudomonas aeruginosa remains the most common respiratory pathogen causing morbidity and mortality ...
Ciprofloxacin is effective for treating pulmonary infection in adult cystic fibrosis patients, and d...
Objectives: Acute viral respiratory illnesses are associated with acquisition of Pseudomonas aerugin...
The optimal antibiotic regimen is unclear in management of pulmonary infections due to pseudomonas a...
Twenty-nine patients with cystic fibrosis received either cefsulodin or a reference agent (tobramyci...
Cystic fibrosis (CF) is the most common lethal hereditary disorder with autosomal recessive heredity...
This review is the third installment in a comprehensive State of the Art series and aims to evaluate...
Monotherapy with pefloxacin, ofloxacin, or ciprofloxacin for acute exacerbations of bron-chopulmonar...
SIGLEAvailable from British Library Document Supply Centre- DSC:DXN1564 / BLDSC - British Library Do...
Cystic fibrosis (CF) is the most common lethal hereditary disorder with autosomal recessive heredity...
Intravenous ciprofloxacin at a daily dosage of 400 mg divided in two doses was administered to 19 pa...
AbstractChronic respiratory infection caused by Pseudomonas aeruginosa is the main driver of morbidi...
Twelve courses of intravenous temocillin were given in combination with an intravenous aminoglycosid...
Abstract Chronic Pseudomonas aeruginosa lung infection in cystic fibrosis (CF) patients is caused by...
The clinical efficacy and safety of ciprofloxacin and ofloxacin were compared in a prospective, rand...
Pseudomonas aeruginosa remains the most common respiratory pathogen causing morbidity and mortality ...
Ciprofloxacin is effective for treating pulmonary infection in adult cystic fibrosis patients, and d...
Objectives: Acute viral respiratory illnesses are associated with acquisition of Pseudomonas aerugin...
The optimal antibiotic regimen is unclear in management of pulmonary infections due to pseudomonas a...
Twenty-nine patients with cystic fibrosis received either cefsulodin or a reference agent (tobramyci...
Cystic fibrosis (CF) is the most common lethal hereditary disorder with autosomal recessive heredity...
This review is the third installment in a comprehensive State of the Art series and aims to evaluate...
Monotherapy with pefloxacin, ofloxacin, or ciprofloxacin for acute exacerbations of bron-chopulmonar...
SIGLEAvailable from British Library Document Supply Centre- DSC:DXN1564 / BLDSC - British Library Do...
Cystic fibrosis (CF) is the most common lethal hereditary disorder with autosomal recessive heredity...
Intravenous ciprofloxacin at a daily dosage of 400 mg divided in two doses was administered to 19 pa...
AbstractChronic respiratory infection caused by Pseudomonas aeruginosa is the main driver of morbidi...
Twelve courses of intravenous temocillin were given in combination with an intravenous aminoglycosid...
Abstract Chronic Pseudomonas aeruginosa lung infection in cystic fibrosis (CF) patients is caused by...