The Paradox in Translational Medicine To the Editor: Advances in laboratory sciences

have raised expectations of discovery of clinically useful biomarkers, but few such new tests have appeared to date. Hortin et al. (1) highlighted several challenges in the translation of promising markers into clinical laboratory tests. Translational medi-cine, which is currently defined as the translation of basic research into practical clinical applications, has great potential to develop and de-liver new tools that may assist pre-vention, diagnosis, and treatment of disease (2). In the field of laboratory medicine, the transfer of promisin