Add to ORKGAbstract Protein misfolding is a general causation of classical conformational diseases and many pathogenic changes that are the result of structural conversion. Here I review recent progress in clinical and computational approaches for each stage of the misfolding process, aiming to present readers an outline for swift comprehen-sion of this field
Proteins are biopolymers that present the particularity to adopt a specific tridimensional structure...
Although intensively researched, the fundamental mechanism of protein misfolding that leads to prote...
Recent findings strongly support the hypothesis that diverse human disorders, including the most com...
Protein misfolding is a general causation of classical conformational diseases and many pathogenic c...
AbstractDiverse human disorders, including several neurodegenerative diseases and systemic amyloidos...
Abstract Substantial progress has been made towards understanding the folding mechanisms of proteins...
For most of proteins to be active, they need well-defined three-dimensional structures alone or in c...
Most proteins fold into their native structure through well defined pathways which involve a limited...
Conformational Protein Diseases (CPDs) comprise over forty clinically and pathologically diverse dis...
Conformational Protein Diseases (CPDs) comprise over forty clinically and pathologically diverse dis...
Protein folding is the process by which a polypeptide chain acquires its functional, native 3D struc...
Abstract: Protein folding in the cell is a tightly regulated process, involving a series of proteins...
Protein aggregation occurs in vivo as a result of improper folding or misfolding. Diverse diseases a...
Diverse human diseases, including various neurodegenerative disorders and amyloidoses, are thought t...
Protein misfolding refers to a process where proteins become structurally abnormal and lose their sp...
Proteins are biopolymers that present the particularity to adopt a specific tridimensional structure...
Although intensively researched, the fundamental mechanism of protein misfolding that leads to prote...
Recent findings strongly support the hypothesis that diverse human disorders, including the most com...
Protein misfolding is a general causation of classical conformational diseases and many pathogenic c...
AbstractDiverse human disorders, including several neurodegenerative diseases and systemic amyloidos...
Abstract Substantial progress has been made towards understanding the folding mechanisms of proteins...
For most of proteins to be active, they need well-defined three-dimensional structures alone or in c...
Most proteins fold into their native structure through well defined pathways which involve a limited...
Conformational Protein Diseases (CPDs) comprise over forty clinically and pathologically diverse dis...
Conformational Protein Diseases (CPDs) comprise over forty clinically and pathologically diverse dis...
Protein folding is the process by which a polypeptide chain acquires its functional, native 3D struc...
Abstract: Protein folding in the cell is a tightly regulated process, involving a series of proteins...
Protein aggregation occurs in vivo as a result of improper folding or misfolding. Diverse diseases a...
Diverse human diseases, including various neurodegenerative disorders and amyloidoses, are thought t...
Protein misfolding refers to a process where proteins become structurally abnormal and lose their sp...
Proteins are biopolymers that present the particularity to adopt a specific tridimensional structure...
Although intensively researched, the fundamental mechanism of protein misfolding that leads to prote...
Recent findings strongly support the hypothesis that diverse human disorders, including the most com...