Natural antimicrobial peptides provide fundamental protection for multi-cellular organisms from microbes, such as Lactoferricin B (Lfcin B). Many studies have shown that Lfcin B penetrates the cell membrane and has intracellular activities. To elucidate the intracellular behavior of Lfcin B, we first used E. coli K12 proteome chips to identify the intracellular targets of Lfcin B. The results showed that Lfcin B binds to two response regulators, BasR and CreB, of the two-component system (TCS). For further analysis, we conducted several in vitro and in vivo experiments and utilized bioinformatics methods. The electrophoretic mobility shift assays and kinase assays indicate that Lfcin B inhibits the phosphorylation of the response regulators...
Lactoferrin is a glycoprotein with two globular lobes, each having two domains. Since the discovery ...
Lactoferrin (LF) is an important antimicrobial and immune regulatory protein present in neutrophils ...
Lactoferricin B is a cationic antimicrobial peptide derived from the N-terminal part of bovine lacto...
Lactoferricin B (LfcinB) is a well-known antimicrobial peptide. Several studies have indicated that ...
Lactoferrin (LF) is a protein with antimicrobial activity, which is conferred in part by two regions...
Lactoferrin (LF) is a protein with antimicrobial activity, which is conferred in part by 2 regions c...
Not AvailableThe study evaluated the in vitro antimicrobial and antibiofilm efficacy of an antimicro...
Lactoferricin includes an 11-amino-acid amphipathic alpha-helical region which is exhibited on the o...
Lactoferrin (LF) is an important immune protein in neutrophils and secretory fluids of mammals. Bovi...
Bovine lactoferrin (BLf) and its derivative peptide lactoferricin B (LfcinB) are known for their ant...
AbstractA synthetic peptide (23 residues) that includes the antibacterial and lipopolysaccharide-bin...
Anti-Microbial Peptides (AMPs) are part of the innate immune defense system and considered as promis...
Lactoferricin (Lfcin), a cationic antimicrobial peptide, was purified by peptic digestion of food gr...
In recent years, the overuse of antibiotics has become very serious. Many pathogenic bacteria have b...
Increased prevalence of antibiotic-resistant bacteria has become a major threat to the health sector...
Lactoferrin is a glycoprotein with two globular lobes, each having two domains. Since the discovery ...
Lactoferrin (LF) is an important antimicrobial and immune regulatory protein present in neutrophils ...
Lactoferricin B is a cationic antimicrobial peptide derived from the N-terminal part of bovine lacto...
Lactoferricin B (LfcinB) is a well-known antimicrobial peptide. Several studies have indicated that ...
Lactoferrin (LF) is a protein with antimicrobial activity, which is conferred in part by two regions...
Lactoferrin (LF) is a protein with antimicrobial activity, which is conferred in part by 2 regions c...
Not AvailableThe study evaluated the in vitro antimicrobial and antibiofilm efficacy of an antimicro...
Lactoferricin includes an 11-amino-acid amphipathic alpha-helical region which is exhibited on the o...
Lactoferrin (LF) is an important immune protein in neutrophils and secretory fluids of mammals. Bovi...
Bovine lactoferrin (BLf) and its derivative peptide lactoferricin B (LfcinB) are known for their ant...
AbstractA synthetic peptide (23 residues) that includes the antibacterial and lipopolysaccharide-bin...
Anti-Microbial Peptides (AMPs) are part of the innate immune defense system and considered as promis...
Lactoferricin (Lfcin), a cationic antimicrobial peptide, was purified by peptic digestion of food gr...
In recent years, the overuse of antibiotics has become very serious. Many pathogenic bacteria have b...
Increased prevalence of antibiotic-resistant bacteria has become a major threat to the health sector...
Lactoferrin is a glycoprotein with two globular lobes, each having two domains. Since the discovery ...
Lactoferrin (LF) is an important antimicrobial and immune regulatory protein present in neutrophils ...
Lactoferricin B is a cationic antimicrobial peptide derived from the N-terminal part of bovine lacto...