Polymorphism in Chinese Patients

0.44 v 0.37, respectively) , the differences were notReports from different ethnic populations failed significant by x2 analysis (P .07 and.09,to show consistent findings on the association of respectively). Furthermore, we did not find thehypertension with insertion/deletion (I /D) trend of decreasing number of DD genotype inpolymorphism of the angiotensin I converting older hypertensive Chinese patients. The resultsenzyme (ACE) gene. In this population indicated a much lower prevalence of ACE/DDassociation study in Chinese, we compared the genotype in Chinese than in Caucasians and adistribution of the ACE genotypes and allele modest association between I/D polymorphism offrequency in 150 healthy controls with normal the ACE gene and hypertension in Chinese. Amblood pressure and 148 hypertensive patients J Hypertens 1997;10:558–561 q 1997 Americancategorized by age. Although the frequencies of Journal of Hypertension, Ltd. homozygote deletion (DD) genotype and deletion allele were greater in Chinese with hypertension KEY WORDS: Angiotensin I-converting enzyme, than in normotensive controls (0.23 vs 0.13 and gene polymorphism, hypertension, Chinese