123I– metaiodobenzylguanidine myocardial scintigraphy

Objectives—123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy is clini-cally used to estimate local myocardial sympathetic nerve damage in some forms of heart disease, autonomic nerve distur-bance in diabetic neuropathy, and distur-bance of the autonomic nervous system in neurodegenerative disease. In the present study, examinations were performed to clarify (1) the proportion of cardiac sym-pathetic nerve disturbance in Parkinson’s disease, (2) the usefulness of 123I-MIBG myocardial scintigraphy to detect sympa-thetic nerve disturbances compared wit