Kyoto University Glyoxylate-Glyooylate System in Yeast

Many investigators have established the importance of the tricarboxylic acid cycle for oxidative processes in yeast. All of the enzymes of the cycle have already been demonstrated in Saccharomyces cerevisiae. However, it has recent-ly been found that isocitritase, the enzyme which degrades isocitrate to glyoxylate and succinate, is contained in baker's yeast'iy). The authors have more recently demonstrated glyoxylic reductase (Reaction I) in several bacteria including Escherichia colt, Aerobacter aerogenes and Pseudomonas fluorescens3>". CHO+TPNH (DPNH)* * +H+---,CH2OH +TPN+(DPN)