Arstila et al. (1) estimated an average diver-sity of 9 3 105 different b chains and 4.5 3 105 different a chains in the human naı̈ve T cell repertoire. To calculate the total T cell repertoire diversity, the b-chain diversity was estimated within a certain variable (V) gene family, Va12 1, comprising 2.5 % of the total a-chain repertoire. Finding in this particular family an estimated total of 6 3 105 different b chains (i.e., two-thirds of the total b-chain repertoire), Arstila et al. suggested that the total T cell receptor (TCR) diversity compris-es at least (6 3 105) 3 40 5 2.4 3 107 different ab combinations (1). The author
[Extract] T cells play a central role in immunity as both regulators and effectors of immune functio...
The T-cell (TCR) repertoire relies on the diversity of receptors composed of two chains, called α an...
doi : 10.1016/j.molimm.2007.02.017International audienceThe size of the available human alphabeta T ...
(a = alpha) Arstila et al. (1) estimated an average diversity of 9 * 10^5 different b chains and 4...
T-Cell Receptors are heterodimeric molecules composed of two hyper-variable protein chains. TCR Dive...
A diverse T cell receptor (TCR) repertoire is essential for adaptive immune responses and is generat...
A diverse T cell receptor (TCR) repertoire is essential for adaptive immune responses and is generat...
The diversity of T-cell receptor (TCR) repertoires is achieved by a combination of two intrinsically...
αβ T cells constitute an important component in the first line of immunologic defense in human skin....
The diversity of T-cell receptor (TCR) repertoires is achieved by a combination of two intrinsically...
The clone size distribution of the human naive T-cell receptor (TCR) repertoire is an important dete...
The nucleotide sequences of 27 T-cell receptor β cDNA clones isolated from a human peripheral lympho...
The clone size distribution of the human naive T-cell receptor (TCR) repertoire is an important dete...
The clone size distribution of the human naive T-cell receptor (TCR) repertoire is an important dete...
T and B cell receptor (TCR and BCR) complementarity determining region 3 (CDR3) genetic diversity is...
[Extract] T cells play a central role in immunity as both regulators and effectors of immune functio...
The T-cell (TCR) repertoire relies on the diversity of receptors composed of two chains, called α an...
doi : 10.1016/j.molimm.2007.02.017International audienceThe size of the available human alphabeta T ...
(a = alpha) Arstila et al. (1) estimated an average diversity of 9 * 10^5 different b chains and 4...
T-Cell Receptors are heterodimeric molecules composed of two hyper-variable protein chains. TCR Dive...
A diverse T cell receptor (TCR) repertoire is essential for adaptive immune responses and is generat...
A diverse T cell receptor (TCR) repertoire is essential for adaptive immune responses and is generat...
The diversity of T-cell receptor (TCR) repertoires is achieved by a combination of two intrinsically...
αβ T cells constitute an important component in the first line of immunologic defense in human skin....
The diversity of T-cell receptor (TCR) repertoires is achieved by a combination of two intrinsically...
The clone size distribution of the human naive T-cell receptor (TCR) repertoire is an important dete...
The nucleotide sequences of 27 T-cell receptor β cDNA clones isolated from a human peripheral lympho...
The clone size distribution of the human naive T-cell receptor (TCR) repertoire is an important dete...
The clone size distribution of the human naive T-cell receptor (TCR) repertoire is an important dete...
T and B cell receptor (TCR and BCR) complementarity determining region 3 (CDR3) genetic diversity is...
[Extract] T cells play a central role in immunity as both regulators and effectors of immune functio...
The T-cell (TCR) repertoire relies on the diversity of receptors composed of two chains, called α an...
doi : 10.1016/j.molimm.2007.02.017International audienceThe size of the available human alphabeta T ...