Pediatric Pituitary Adenomas

● Context.—Pituitary adenomas are relatively rare occur-rences in the pediatric population, and there are few stud-ies documenting the profile of these tumors in this age group. Objective.—To study the clinical and pathologic features of pediatric pituitary adenomas in conjunction with a re-view of the available literature. Design.—A retrospective clinicopathologic review of 20 pediatric patients (younger than 20 years of age) with pi-tuitary adenomas resected during a 24.5-year period (1981–2005). Results.—A total of 20 patients, including 12 females and 8 males, comprise the study group. Mean age at onset of symptoms was 14.0 years (range, 5–18 years). Four pa-tients had onset of symptoms before the age of 12 years