LETTERS TO THE EDITOR

Grading system for inflammation in ulcerative colitis EDITOR,—Geboes et al described a grading system for inflammation in ulcerative colitis and carried out rigorous assessment of the reproducibility of this system (Gut 2000;47:404–9). This is a very useful study which fills a void in the histopathology assessment of ulcerative colitis. However, now that this system has been described, its use in clinical practice and clinical trials needs to be considered. Many of the features that Geboes et al have used in their grading system are described as continuous spectra—for example, chroni