The Future of Randomised Cont

ro rg om Gr the management of genitourinary trauma. For the endour-One of the ethical prerequisites for an RCT is that equipoise surgical and nonsurgical treatments (eg, scrotal orchiectomy EURO P E AN URO LOG Y 6 6 ( 2 0 1 4) 1 – 3 ava i lable at www.sciencedirect.com journal homepage: www.europeanurology.comcontrol for selection bias, and <10 % reporting analysesologic management of stone disease, a recent study found an apparent abundance of 106 RCTs over a 10-yr period, but their quality was low, with <15 % reporting appropriate randomisation and allocation concealment techniques to vs gonadotropin-releasing hormone analogues/antagonists) challenge biases and expectations of all stakeholders and require professional training and communication skills among physician recruiters to reach equipoise [7]. This lack of equipoise may have contributed to the failure of theThe shortfall relates both to the quantity and quality of RCTs and varies by subspecialty. For instance, in paediatric urology, a systematic review identified only 77 low- to medium-quality RCTs in total between 1960 and 2004. Based on the 2013 EAU guidelines, no RCT currently informs concerning the treatment alternatives exists in the shared decision making between patients and physicians. Several important trials in urology have been challenging with regard to equipoise because of the very different nature an