Proteinuria during the q-hour period following exercise’

during the q-hour period following exercise. J. Appl. Physiol. 15(4) : 592-594. I g6o.-The urine of IO football players, collected for 24 hours following a practice game, was found to contain 2.3-15.2 times as much protein as urine collected following a period of rest. No changes were noted on electro-phoresis of the serum proteins. The renal clearance of serum albumin increased more than the clearance of serum globulins following exercise, but in both the control and post-exercise specimens the clearance of globulins and percentage of glob-ulins in the urine usually exceeded these values for albumin. Considerable variation in the excretion of proteins was noted among individual subjects in the control period; as protein excretion increased following exercise, the protein excretion patterns became more uniform in these subjects. Compared to the previously described exercise proteinuria which occurs immediately following exercise, this second phase is charac-terized by less intense protein excretion and longer duration. T HE PROTEINURIA which regularly follows strenuous exercise is of interest not only as a finding of possible clinical importance, but also because it is one of the few types of proteinuria which can be regularly produced without the use of toxic doses of drugs or surgical pro-cedures. In addition to numerous reports of the types of exercise in which proteinuria and abnormal urine sediments are found (r-3), Javitt and Miller (4) have reported de-creases in the glomerular filtration rate and blood pH associated with the appearance of proteinuria. Nebdal and Seliger (5) studied the amount and electrophoretic pattern of the urine protein excreted. The latter two studies deal with the changes seen in the immediate post-exercise period. This report deals with the clearance of serum proteins by the kidney in the 24-hour period following exercise