Add to ORKGWe have investigated extrahepatic metabolism of propofol in 10 patients undergoing orthotopic liver transplantation (group 1) (mean age 38 yr, mean weight 60 (SD 7) kg) and compared it with that in 10 patients without liver dysfunction undergoing extrahepatic abdominal surgery (group 2) (mean age 56 yr, mean weight 68 (11) kg). A single i.v. bolus dose of propofol 0.5 mg kg~ ' was injected into a peripheral vein 5 min after the beginning of the anhepatic phase in group 1 and 60 min after the induction of anaesthesia in group 2. Arterial bloo
Evidence suggests that propofol infusion syndrome (PRIS) is caused by an altered mitochondrial funct...
Background. The right ventricular ejection fraction pulmonary artery catheter (RVEF-PAC) has been wi...
Objectives: To present a rare case of propofol-induced hepatitis.Materials and methods: A 59-year ol...
Propofol is a rapidly acting general anesthetic which is widely used as an intravenous agent for bot...
BACKGROUND: Propofol is an anaesthetic that resembles α-tocopherol and it has been suggested that it...
Background. Liver transplantation leads to liver ischemia/reperfusion (I/R) injury, resulting in ear...
OBJECTIVE: Results from clinical pharmacokinetic studies of propofol indicate that this i.v. anaesth...
BACKGROUND: Sevoflurane is metabolized by cytochrome P450 and produces inorganic fluoride. The anhep...
The incidence of drug-induced acute liver failure is increasing. A number of drugs can inhibit mitoc...
International audiencePropofol has shown antioxidant properties, but no study has focused on liver r...
BACKGROUND: Remote Pulmonary injuries after hepatic reperfusion are frequently caused by reactive ox...
Background Maintaining adequate perioperative hepatic blood flow (HBF) supply is essential for pres...
The effect of propofol on the hepatic and extrahepatic conjugation enzyme systems was assessed in vi...
Objective To investigate the effect of cardiac output and liver blood flow on propofol concentration...
OBJECTIVE: The main objective of this study was to evaluate the effect of switching from parenteral ...
Evidence suggests that propofol infusion syndrome (PRIS) is caused by an altered mitochondrial funct...
Background. The right ventricular ejection fraction pulmonary artery catheter (RVEF-PAC) has been wi...
Objectives: To present a rare case of propofol-induced hepatitis.Materials and methods: A 59-year ol...
Propofol is a rapidly acting general anesthetic which is widely used as an intravenous agent for bot...
BACKGROUND: Propofol is an anaesthetic that resembles α-tocopherol and it has been suggested that it...
Background. Liver transplantation leads to liver ischemia/reperfusion (I/R) injury, resulting in ear...
OBJECTIVE: Results from clinical pharmacokinetic studies of propofol indicate that this i.v. anaesth...
BACKGROUND: Sevoflurane is metabolized by cytochrome P450 and produces inorganic fluoride. The anhep...
The incidence of drug-induced acute liver failure is increasing. A number of drugs can inhibit mitoc...
International audiencePropofol has shown antioxidant properties, but no study has focused on liver r...
BACKGROUND: Remote Pulmonary injuries after hepatic reperfusion are frequently caused by reactive ox...
Background Maintaining adequate perioperative hepatic blood flow (HBF) supply is essential for pres...
The effect of propofol on the hepatic and extrahepatic conjugation enzyme systems was assessed in vi...
Objective To investigate the effect of cardiac output and liver blood flow on propofol concentration...
OBJECTIVE: The main objective of this study was to evaluate the effect of switching from parenteral ...
Evidence suggests that propofol infusion syndrome (PRIS) is caused by an altered mitochondrial funct...
Background. The right ventricular ejection fraction pulmonary artery catheter (RVEF-PAC) has been wi...
Objectives: To present a rare case of propofol-induced hepatitis.Materials and methods: A 59-year ol...