Raman Scattering Microscopy Correlated with Super-resolution Fluorescence Microscopy

eolites are porous crystalline solids with pores of molecular dimensions, providing size and shape selectivity in catalysis.14 Acid mordenites (H-MORs) are typical catalysts used in the petrochemical industry, mostly for cracking, isomerization, and alkylation reactions. The Brønsted acidic framework hydroxyls are lining the porous network that consists of main chan-nels (6.5 7.0 Å2) and small channels (5.7 2.6 Å2) oriented along the crystallographic c-axis with side pockets (3.4 4.8 Å2) along the b-axis. The side pockets are too small for most organic molecules, resulting in a qua-si-unidirectional microporous system that makes as-synthesized H-MOR susceptible to mass transport limitations and rapid deactivation.5,6 Optimization of the catalytic performance often relies on postsynthetic treatments such as dealumination that re-duces the framework aluminum content and also introduces mesoporosity, thus enhancing molecular transport and slowing thedeactivationbycoke formation. Typically, dealumination involves repeated chemical (e.g., acid leaching) and hydrothermal (steaming) treatments that have complex implications on both compositional and structural properties, such as acid site density, accessibility, pore network, etc.7,8 Currently, optimization of H-MOR perfor-mance and of catalysts in general is largely based on trial-and-error experiments using bulk catalyst samples, without much insight at the relevant length scales since tools cap-able of looking beyond the crystal surface * Address correspondence t