Colon Cancer to Biotherapeutics and

Drug resistance is a major obstacle in cancer treatment cytotoxic, or targeted therapeutics. Being an antiapoptot cancer cells, MKP1 phosphatase might be targeted for ove bitor-ors t PI-3 is at oma c (comb %, P ressio n tho ics, 5 ta sho impli prov Introdu Drug r could be treatmen biologica tification standing insights approach MKP1 1, dual-s tified re chemoth ast can-nt with yclines clitaxel; cer cells MKP-1 ed lung cance of rexpres-ast can-cer, and effect is pression 11). ant part horylat-poptoic sion in cancer cells increased apoptosis (12, 14). Among apoptotic action. Inducible MKP1 expression blocked is (17), whereas iates JNK activa-restingly, MKP-