Ventilatory response to hypoxia and hypercapnia in cats living at high altitude

response to hypoxia and hypempnia in cats lz’ving at high altitude. J. Appl. Physiol. 27(6) : 834-836. 1969,-Man born and living at high altitude ventilates less in response to hypoxia than his sea-level counterpart. In contrast, we found the ventilation of 6 cats native to high altitude and 10 sea-level cats to be equally vigorous in response to acute hypoxia. In these decerebrate, unanesthetized animals, ventilatory acclimatization to chronic hypoxia was ap-parent from the shift of the’hypoxic CO2 response curve to a lower pace, l regulation of respiration; peripheral chemoreceptors; adaptation; acclimatization to chronic hypoxia MAN native to high altitude breathes less vigorously in response to acute hypoxia than his lowland counterpart (6, 10, 13, 14). This h yposensitivity to hypoxia could represent either a decreased neural output from periphera