COMBINED CLINIC THE LYMPHOMAS: COMBINED CLINIC AT THE COLLEGE OF

DR. ALFRED GELLHORN: Today we discuss a group of diseases, the lym-phomas, various aspects of which are being productively investigated in many parts of the world. During our presentation we will introduce summaries of some phases of these investigations not only because they illuminate hitherto obscure facets of the lymphomas, but also because they have relevance to other malignant neoplastic diseases and increase our understanding of biologic phe-nomena in normal cells as well. To set the stage for certain issues to be highlighted, I would like to offer a kaleidoscopic review of the natural history of the malignant lymphomas. Hodgkin's disease and lymphosarcoma are the tumors encompassed by this designation. The precise differentiation between these two major entities rests on histologic characterization, despite many differences in the clinical course. Both Hodgkin's disease and lymphosarcoma have been further fragmented morphologically, but in the case of the former, such additional classifications carry no implications regarding the course of the disease and are therefore o