Add to ORKGAbstract: In the present article the effect of kosmotrope compounds, i.e. systems having the capability to stabilize biological macromolecules, is investigated by using complementary techniques. The attention is focused on the kosmotrope character of trehalose, a glucose disaccharide, compared to its homologous maltose and sucrose. Complementary techniques of neutron scattering, such as Inelastic Neutron Scattering (INS) and Quasi Elastic Neutron Scattering (QENS) allow to point out the capability of trehalose to strongly affect both the structural and dynamical properties of water. Finally the stabilization effect of trehalose on a well know protein, lysozyme, is studied as a function of temperature by Small Angle Neutron Scattering (SANS)
Neutron scattering techniques represent a powerful tool for characterizing both the structure and dy...
The effect of the sugars sucrose, glucose, and trehalose on the structural and colloidal stability ...
The molecular structure of an aqueous solution of the disaccharide trehalose (C12H22O11) has been st...
The sugar molecule trehalose has been proven to be an excellent stabilizing cosolute for the preserv...
In this contribution the effects of the homologous disaccharides trehalose and sucrose on both water...
The understanding of biomolecular interactions with water and co-solutes opens up further understand...
The sugar molecule trehalose has been proven to be an excellent stabilizing cosolute for the preserv...
The understanding of biomolecular interactions with water and co-solutes can lead to greater knowled...
Maintaining protein stability is essential in research involving proteins, especially when studying ...
The ability of a wide class of organisms to reversibly go through cycles of suspended life and activ...
Understanding of how the stabilization mechanism of trehalose operates on biological molecules again...
We combined broad-band depolarized light scattering and infrared spectroscopies to study the propert...
Trehalose, commonly found in living organisms, is believed to help them survive severe environmental...
Abstract: Immobilization of proteins and other biomolecules in saccharide matrices leads to a series...
The observation made by early naturalists that some organisms could tolerate extreme environmental c...
Neutron scattering techniques represent a powerful tool for characterizing both the structure and dy...
The effect of the sugars sucrose, glucose, and trehalose on the structural and colloidal stability ...
The molecular structure of an aqueous solution of the disaccharide trehalose (C12H22O11) has been st...
The sugar molecule trehalose has been proven to be an excellent stabilizing cosolute for the preserv...
In this contribution the effects of the homologous disaccharides trehalose and sucrose on both water...
The understanding of biomolecular interactions with water and co-solutes opens up further understand...
The sugar molecule trehalose has been proven to be an excellent stabilizing cosolute for the preserv...
The understanding of biomolecular interactions with water and co-solutes can lead to greater knowled...
Maintaining protein stability is essential in research involving proteins, especially when studying ...
The ability of a wide class of organisms to reversibly go through cycles of suspended life and activ...
Understanding of how the stabilization mechanism of trehalose operates on biological molecules again...
We combined broad-band depolarized light scattering and infrared spectroscopies to study the propert...
Trehalose, commonly found in living organisms, is believed to help them survive severe environmental...
Abstract: Immobilization of proteins and other biomolecules in saccharide matrices leads to a series...
The observation made by early naturalists that some organisms could tolerate extreme environmental c...
Neutron scattering techniques represent a powerful tool for characterizing both the structure and dy...
The effect of the sugars sucrose, glucose, and trehalose on the structural and colloidal stability ...
The molecular structure of an aqueous solution of the disaccharide trehalose (C12H22O11) has been st...