The genomic RNA ofpestiviruses is translated into a large polyprotein that is cleaved into a number ofproteins. The structural proteins are N terminal in this polyprotein and include three glycoproteins called EO, El, and E2 on the basis of the order in which they appear in the polyprotein. Using pulse-chase experiments, we show that a pestiviral glycoprotein precursor, E012, is formed that is processed into EO, El, and E2 in an ordered fashion. Processing is initiated by a nascent cleavage between the capsid and the translocated E012 followed by cleavage at the C terminus ofE2. E012 is then rapidly cleaved to form E01 and E2. After E2 is released from the precursor, E01 is processed into EO and El. To identify the sites of cleavage, the N ...
AbstractEnvelope glycoprotein E2 (gp51 to gp54) is the major neutralizing antigen of pestiviruses, w...
a) The RNA genome of viruses in the genus Aphthovirus, in which FMDV is the prototypic member, encod...
African swine fever (ASF) virus is a large DNA virus that shares the striking icosahedral symmetry o...
The genomic RNA of pestiviruses is translated into a large polyprotein that is cleaved into a number...
Pestiviruses belong to the family Flaviviridae with the most well-known being Bovine Viral Diarrhoea...
Pestiviruses, which include economically important animal pathogens such as bovine viral diarrhea vi...
swine fever virus (ASFV) genome that encodes a polyprotein of 62 kDa (pp62). Antisera raised against...
Pestiviruses are pathogens of cloven-hoofed animals, belonging to the Flaviviridae. The pestiviral p...
SummaryEnveloped viruses have developed various adroit mechanisms to invade their host cells. This p...
The structural part of the hepatitis C virus (HCV) genome ncodes a capsid protein, C, and two envelo...
International audiencePestiviruses, which belong to the Flaviviridae family of RNA viruses, are impo...
AbstractClass II fusion proteins encoded by tick-borne encephalitis virus (TBEV), dengue virus, and ...
Enveloped viruses have developed various adroit mechanisms to invade their host cells. This process ...
We have used a computer program to scan the entire sequence of viral polyproteins for eucaryotic sig...
E(rns) is a pestivirus envelope glycoprotein indispensable for virus attachment and infection of tar...
AbstractEnvelope glycoprotein E2 (gp51 to gp54) is the major neutralizing antigen of pestiviruses, w...
a) The RNA genome of viruses in the genus Aphthovirus, in which FMDV is the prototypic member, encod...
African swine fever (ASF) virus is a large DNA virus that shares the striking icosahedral symmetry o...
The genomic RNA of pestiviruses is translated into a large polyprotein that is cleaved into a number...
Pestiviruses belong to the family Flaviviridae with the most well-known being Bovine Viral Diarrhoea...
Pestiviruses, which include economically important animal pathogens such as bovine viral diarrhea vi...
swine fever virus (ASFV) genome that encodes a polyprotein of 62 kDa (pp62). Antisera raised against...
Pestiviruses are pathogens of cloven-hoofed animals, belonging to the Flaviviridae. The pestiviral p...
SummaryEnveloped viruses have developed various adroit mechanisms to invade their host cells. This p...
The structural part of the hepatitis C virus (HCV) genome ncodes a capsid protein, C, and two envelo...
International audiencePestiviruses, which belong to the Flaviviridae family of RNA viruses, are impo...
AbstractClass II fusion proteins encoded by tick-borne encephalitis virus (TBEV), dengue virus, and ...
Enveloped viruses have developed various adroit mechanisms to invade their host cells. This process ...
We have used a computer program to scan the entire sequence of viral polyproteins for eucaryotic sig...
E(rns) is a pestivirus envelope glycoprotein indispensable for virus attachment and infection of tar...
AbstractEnvelope glycoprotein E2 (gp51 to gp54) is the major neutralizing antigen of pestiviruses, w...
a) The RNA genome of viruses in the genus Aphthovirus, in which FMDV is the prototypic member, encod...
African swine fever (ASF) virus is a large DNA virus that shares the striking icosahedral symmetry o...