Original Article

Implication for health policy/practice/research/medical education: Lower effect of povidone iodine may be the result of the lack of deep penetration of this drug into the corneal stroma, but other factors may be involved. 1. Background Corneal ulcer is an infectious condition, and follows the destructive influence of bacteria, viruses and fungi (1). This disease is a common cause of blindness and finan-cial loss in developing countries, and leads to corneal perforation and blindness if not treated properly (2). Staphylococcus species, particularly Staphylococcus au-Background: Corneal ulcer is a common cause of blindness in developing countries, as itleads to corneal perforation and blindness if not properly treated. Objectives: This study aimed to determine the effects of intraocular 5 % and 10 % topical povi-done iodine in the treatment of bacterial corneal ulcer in a rabbit model, comparing the effectiveness of vancomycin and cefazolin eye drops