RESEARCH Organization of brain netw n n

Full list of author information is available at the end of the articleautism, he noticed that some of the symptoms observed in children were shared at sub-threshold levels by their parents [1]. This original observation has been con-firmed by several studies [2,3]. Today, the predominant view is that autism spectrum disorder (ASD) is not an all-or-nothing condition; instead, its severity is graded and can be quantified through several diagnostic suggest that ASD constitutes the extreme of a dimension traversing through the entire population [7,8]. This has led to the development of behavioural measures seeking to evaluate related traits in the general population, such as the Social Responsiveness Scale (SRS) [7], and to use this dimensional approach to study ASD [7-9]. There is increasing evidence that ASD could be a con-dition of altered brain connectivity [10-13], including a reduced corpus callosum [14] and diminished long-range functional connectivity [12,15,16], producing a system that is ineffective for integrating informatio