Add to ORKGDecision Editor: Stephen Kritchevsky, PhD Background. Caloric restriction (CR), energy intake reduced below ad libitum (AL) intake, increases life span in many species. The implications for humans can be clarified by randomized controlled trials of CR. Methods. To determine CR’s feasibility, safety, and effects on predictors of longevity, disease risk factors, and quality of life in nonobese humans aged 21–51 years, 218 persons were randomized to a 2-year intervention designed to achieve 25 % CR or to AL diet. Outcomes were change fro
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, p...
Demographers have observed in several human popula-tions that the environment can have a major effec...
Striving for longevity is neither a recent human desire nor a novel scientific field. The first arti...
Decision Editor: Stephen Kritchevsky, PhD Background. Caloric restriction (CR), energy intake reduce...
Caloric restriction (CR), energy intake reduced below ad libitum (AL) intake, increases life span in...
Obesity has been linked to increased risk of disease and a lower life expectancy. Emerging research ...
Background: Global dietary patterns have gradually shifted toward a 'western type' with progressive ...
Demographers have observed in several human popula-tions that the environment can have a major effec...
Caloric restriction (CR) is a strategy that attenuates aging in multiple nonhuman species. The Compr...
Calorie restriction (CR) retards aging and extends mean and maximal life span in most species tested...
Calorie restriction (CR) is as close to a real fountain of youth as any known technique is. Caloric ...
permits unrestricted use, distribution, and reproduction in any medium, provided the original work i...
Excess calorie consumption is associated with metabolic disorders and increased incidence of morbidi...
Context: Prolonged calorie restriction increases life span in rodents. Whether prolonged calorie res...
Calorie restriction (CR) is a potent modulator of longevity in multiple species. A growing body of e...
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, p...
Demographers have observed in several human popula-tions that the environment can have a major effec...
Striving for longevity is neither a recent human desire nor a novel scientific field. The first arti...
Decision Editor: Stephen Kritchevsky, PhD Background. Caloric restriction (CR), energy intake reduce...
Caloric restriction (CR), energy intake reduced below ad libitum (AL) intake, increases life span in...
Obesity has been linked to increased risk of disease and a lower life expectancy. Emerging research ...
Background: Global dietary patterns have gradually shifted toward a 'western type' with progressive ...
Demographers have observed in several human popula-tions that the environment can have a major effec...
Caloric restriction (CR) is a strategy that attenuates aging in multiple nonhuman species. The Compr...
Calorie restriction (CR) retards aging and extends mean and maximal life span in most species tested...
Calorie restriction (CR) is as close to a real fountain of youth as any known technique is. Caloric ...
permits unrestricted use, distribution, and reproduction in any medium, provided the original work i...
Excess calorie consumption is associated with metabolic disorders and increased incidence of morbidi...
Context: Prolonged calorie restriction increases life span in rodents. Whether prolonged calorie res...
Calorie restriction (CR) is a potent modulator of longevity in multiple species. A growing body of e...
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, p...
Demographers have observed in several human popula-tions that the environment can have a major effec...
Striving for longevity is neither a recent human desire nor a novel scientific field. The first arti...