Adipose tissue cellularity and lipolysis. Response to exercise and cortisol treatment. J.Clin.Invest. 56

  • E. W. Askew
  • R. L. Huston
  • C. G. Plopper
  • A. L. Hecker
Publication date
January 1975

Abstract

to 13 wk of intensive treadmill running to study the effect of exercise on adipose tissue cellularity and lipoly-sis. Untrained controls of the same age remained seden-tary in their cages for the duration of the experiment. Adipocyte numbers were similar in epididymal fat pads from trained and untrained rats (12.7+1.3 X 10f vs. 15.3±1.3 X 10 ' cells/pad), however trained rats had smaller fat pads containing smaller cells (0.09±0.01 vs. 0.20±0.04 lyg triglyceride/cell). Adipocytes from trained rats possessed greater epinephrine-sensitive lipase ac-tivity than sedentary rats on a per cell, per milligram protein, per gram adipose tissue, or per fat pad basis. Although the smaller cells of the trained rats had greater epinephrine-sensitive...

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