Add to ORKGABSTRACT-The benzoic acid derivatives of retinoic acid, often referred to as arotinoids, are synthetic retinoids that possess some of the properties of vitamin A. In general, these retinoids have more favorable therapeutic ratios, based on acute toxicity in adults, than all-trans-retinoic acid in cancer chemoprevention. In the present study, a single dose of (E)-4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propen-1-yl)benzoic acid (Ro 13-7410; arotinoic acid), ethyl-(E)-4-(2-(5,6,7,8-tetrahydro
The retinoid-related molecules (RRMs) ST1926 [(E)-3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic ac...
Retinoids, particularly 13-cis-retinoic acid, have shown great promise against a number of benign, b...
A class of less toxic retinoids, called heteroarotinoids, was evaluated for their molecular mechanis...
Retinoids are a class of compounds with structural similarity to vitamin A. These compounds inhibit ...
In this report we will describe the preparation and the biological activity of a novel class of hete...
ventive agents for experimental carcinogenesis of many target organs including mammary gland, urinar...
Five arotinoids have been compared with all-trans- and 13-cisretinoic acids for their ability to pro...
Increasing emphasis has been placed on chemoprevention as understanding of the genetic and molecular...
The retinoids, natural or synthetic derivatives of vitamin A, exhibit a variety of biological effect...
Human embryogenesis and ensuing adult homeostasis are directed by the complex interplay of a wide ra...
Vitamin A is essential for normal growth and development. Epidemiology and laboratory studies sugges...
All-trans retinoic acid is a morphogen during embryogenesis and a teratogen. Cancer is an error of d...
Vitamin A is essential for normal cellular growth and differentiation. A vast amount of laboratory d...
Investigation of retinoids for anticancer activity in humans, either in the chemopreventive or treat...
Retinoids are a class of natural and synthetic vitamin A analogs structurally related to all-trans-...
The retinoid-related molecules (RRMs) ST1926 [(E)-3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic ac...
Retinoids, particularly 13-cis-retinoic acid, have shown great promise against a number of benign, b...
A class of less toxic retinoids, called heteroarotinoids, was evaluated for their molecular mechanis...
Retinoids are a class of compounds with structural similarity to vitamin A. These compounds inhibit ...
In this report we will describe the preparation and the biological activity of a novel class of hete...
ventive agents for experimental carcinogenesis of many target organs including mammary gland, urinar...
Five arotinoids have been compared with all-trans- and 13-cisretinoic acids for their ability to pro...
Increasing emphasis has been placed on chemoprevention as understanding of the genetic and molecular...
The retinoids, natural or synthetic derivatives of vitamin A, exhibit a variety of biological effect...
Human embryogenesis and ensuing adult homeostasis are directed by the complex interplay of a wide ra...
Vitamin A is essential for normal growth and development. Epidemiology and laboratory studies sugges...
All-trans retinoic acid is a morphogen during embryogenesis and a teratogen. Cancer is an error of d...
Vitamin A is essential for normal cellular growth and differentiation. A vast amount of laboratory d...
Investigation of retinoids for anticancer activity in humans, either in the chemopreventive or treat...
Retinoids are a class of natural and synthetic vitamin A analogs structurally related to all-trans-...
The retinoid-related molecules (RRMs) ST1926 [(E)-3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic ac...
Retinoids, particularly 13-cis-retinoic acid, have shown great promise against a number of benign, b...
A class of less toxic retinoids, called heteroarotinoids, was evaluated for their molecular mechanis...