Clinical Trials of Potential Cognitive-Enhancing Drugs in Schizophrenia:What Have We Learned So Far? RichardS.E.Keefe1,*,RobertW.Buchanan2, StephenR.Marder3,NinaR.Schooler4,AshishDugar5,MilanaZivkov6, and

In light of the number of studies conducted to examine the treatment of cognitive impairment associated with schizo-phrenia (CIAS), we critically reviewed recent CIAS trials. Trials were identified through searches of the website ‘‘www.clinicaltrials.gov’ ’ using the terms ‘‘schizophrenia AND cognition,’ ’ ‘‘schizophrenia AND neurocognition,’’ ‘‘schizophrenia AND neurocognitive tests,’ ’ ‘‘schizophreni