Outcome of lung transplantatio

10; a patie, infe rtion European Journal of Cardio-thoracic Sutransplantation in this older cohort. Methods: Between January 1990 and July 2009, 142 patients underwent lung transplantation at our institution. A total of 15 patients receiving heart/lung transplantation and one patient declining research participation were excluded. As many as 126 patients were analyzed in two groups: <60 and 60 years old. Results: There were 65 females (52%) and 61 males (48%). A total of 53 patients (42%) underwent bilateral sequential lung transplantation and 73 patients single-lung transplantation (58%). Median age at transplanta-tion was 55.3 years (range, 21.6—73.1 years) with 94 patients <60 years (75%) and 32 patients 60 years (25%). Median follow-up was 4.3 years (range, 0—17.8 years). Overall survival at 30 days was 93.7 % with no difference between age groups ( p = 0.95). There was no difference between the groups for in-hospital, postoperative complications ( p = 0.86), or unplanned readmission rates within 90 days of the hospitalization ( p = 0.26). Postoperative pulmonary function (forced expiratory volume in 1 s (FEV1) % predicted) at transplant, 4 weeks, 3 months, and 6months after transplantation was not different between groups (p = 0.93). No difference in long-term survival was observed ( p = 0.59), with 5-year survival of 52.2 % for patients<60 years and 47.3 % for patients60 years. Overall, 20 patients developed bronchiolitis obliterans syndrome and 13 posttransplant lymphoproliferative disease, which was not statistically different between age groups ( p = 0.87, p = 0.37, respectively). Conclusion: Increased age of 60 years and greater, in highly selected patients, does not appear to have a significant impact on the short-or long-term outcome in patients undergoing lung transplantation. Judicious selection of older patients, who are otherwise excellent candidates for lung transplantation, remains a reasonable option