Patient Outcomes Study

cystatin C and creatinine-based estimations of glomer-ular filtration rate (eGFR), including the Chronic Kid-ney Disease–Epidemiology (CKD-EPI) equation, in acute coronary syndrome (ACS) patients with (STE-ACS) or without (NSTE-ACS) ST elevation in a large contemporary ACS population. METHODS: Concentrations of cystatin C and creatinine, as well as eGFR at randomization, were measured in 16 401 patients in the Platelet Inhibition and Patient Outcomes (PLATO) study and evaluated as predictors of the composite end point of cardiovascular death or myocardial infarction within 1 year. Two Cox propor-tional hazards models were used, the first adjusting for clinical characteristics and the second for clinical char-acteristics plus the biomarkers N-terminal pro–B-typ