Background Cerebral white matter lesions (WML) have been found in normal aging, vascular disease and several neuropsychiatric conditions. Correlations of WML with clinical parameters in BD have been described, but not with the number of affective episodes, illness duration, age of onset and Body Mass Index in a well characterized group of euthymic bipolar adults. Herein, we aimed to evaluate the associations between bipolar course of illness parameters and WML measured with volumetric analysis. Methods In a cross-sectional study 100 euthymic individuals with BD as well as 54 healthy controls (HC) were enrolled to undergo brain magnetic resonance imaging using 3T including a FLAIR sequence for volumetric assessment of WML-load using FSL-soft...
White matter (WM) abnormalities are proposed as potential endophenotypic markers of bipolar disorder...
Converging evidence suggests that bipolar disorder (BD) is associated with white matter (WM) abnorma...
Fronto-limbic white matter (WM) abnormalities are assumed to lie at the heart of the pathophysiology...
Background: Cerebral white matter lesions (WML) have been found in normal aging, vascular disease an...
Cerebral white matter lesions (WML) have been found in normal aging, vascular disease and several ne...
Cerebral white matter lesions (WML) have been found in normal aging, vascular disease and several ne...
Background and Aims Converging evidence from a number of neuroimaging techniques suggests that bipol...
BACKGROUND: Increased rates of white matter hyperintense lesions have been reported in mood disorder...
Abnormal frontal white matter tracts in bipolar disorder: a diffusion tensor imaging study Several l...
Objectives: Magnetic resonance imaging (MRI) studies have reported an increased frequency of white m...
BACKGROUND: There is substantial inconsistency in results of brain structural magnetic resonance ima...
Background: Bipolar disorder (BD) is characterized by recurrent mood episodes that may progress over...
OBJECTIVES: Functional and postmortem studies suggest that the orbitofrontal cortex (OFC) is involv...
OBJECTIVES: Functional and postmortem studies suggest that the orbitofrontal cortex (OFC) is involve...
Converging evidence suggests that bipolar disorder (BD) is associated with white matter (WM) abnorma...
White matter (WM) abnormalities are proposed as potential endophenotypic markers of bipolar disorder...
Converging evidence suggests that bipolar disorder (BD) is associated with white matter (WM) abnorma...
Fronto-limbic white matter (WM) abnormalities are assumed to lie at the heart of the pathophysiology...
Background: Cerebral white matter lesions (WML) have been found in normal aging, vascular disease an...
Cerebral white matter lesions (WML) have been found in normal aging, vascular disease and several ne...
Cerebral white matter lesions (WML) have been found in normal aging, vascular disease and several ne...
Background and Aims Converging evidence from a number of neuroimaging techniques suggests that bipol...
BACKGROUND: Increased rates of white matter hyperintense lesions have been reported in mood disorder...
Abnormal frontal white matter tracts in bipolar disorder: a diffusion tensor imaging study Several l...
Objectives: Magnetic resonance imaging (MRI) studies have reported an increased frequency of white m...
BACKGROUND: There is substantial inconsistency in results of brain structural magnetic resonance ima...
Background: Bipolar disorder (BD) is characterized by recurrent mood episodes that may progress over...
OBJECTIVES: Functional and postmortem studies suggest that the orbitofrontal cortex (OFC) is involv...
OBJECTIVES: Functional and postmortem studies suggest that the orbitofrontal cortex (OFC) is involve...
Converging evidence suggests that bipolar disorder (BD) is associated with white matter (WM) abnorma...
White matter (WM) abnormalities are proposed as potential endophenotypic markers of bipolar disorder...
Converging evidence suggests that bipolar disorder (BD) is associated with white matter (WM) abnorma...
Fronto-limbic white matter (WM) abnormalities are assumed to lie at the heart of the pathophysiology...