The functions of the FoxO family proteins, in particular their transcriptional activities, are modulated by post-translational modifi-cations (PTMs), including phosphorylation, acetylation, ubiquitination, methylation and glycosylation. These PTMs occur in response to different cellular stresses, which in turn regulate the subcellular localization of FoxO family proteins, as well as their half-life, DNA binding, transcriptional activity and ability to interact with other cellular proteins. In this review, we summarize the role of PTMs of FoxO family proteins in linking their biological and functional relevance with various diseases
Post-Translational Modifications (PTMs) may occur at any stage following the translation process in ...
FoxO3 is a member of the forkhead class of transcription factors and plays a major role in the regul...
FOXO transcription factors are involved in a variety of biological processes including cell cycle re...
The functions of the FoxO family proteins, in particular their transcriptional activities, are modul...
The Forkhead box O (FOXO) family transcription factors play critical roles in a series of cellular p...
Abstract.- The transcription factor Forkhead box O 1 (FOXO1) is a key regulator of metabolic process...
AbstractThe FOXO forkhead transcription factors are involved in metabolism control, cell survival, c...
FOXO transcription factors play an important role in essential biological processes such as differen...
The FOXO transcription factors play a critical role in the oxidative stress-induced neuronal cell de...
SummaryFoxO transcription factors regulate the transcription of genes that control metabolism, cellu...
[[abstract]]FOXO3a is a transcription factor of the FOXO family. The FOXO proteins participate in mu...
FOXO (Forkhead box, class O) proteins are transcriptional regulators ubiquitously expressed in mamma...
Modulation FOXO transcription factor activities can lead to a variety of cellular outputs resulting ...
Phosphorylation of FOXO transcription factors is one of the key mechanisms involved in the regulatio...
Under a Creative Commons license.Transcription factors of the forkhead box, class O (FoxO) family ar...
Post-Translational Modifications (PTMs) may occur at any stage following the translation process in ...
FoxO3 is a member of the forkhead class of transcription factors and plays a major role in the regul...
FOXO transcription factors are involved in a variety of biological processes including cell cycle re...
The functions of the FoxO family proteins, in particular their transcriptional activities, are modul...
The Forkhead box O (FOXO) family transcription factors play critical roles in a series of cellular p...
Abstract.- The transcription factor Forkhead box O 1 (FOXO1) is a key regulator of metabolic process...
AbstractThe FOXO forkhead transcription factors are involved in metabolism control, cell survival, c...
FOXO transcription factors play an important role in essential biological processes such as differen...
The FOXO transcription factors play a critical role in the oxidative stress-induced neuronal cell de...
SummaryFoxO transcription factors regulate the transcription of genes that control metabolism, cellu...
[[abstract]]FOXO3a is a transcription factor of the FOXO family. The FOXO proteins participate in mu...
FOXO (Forkhead box, class O) proteins are transcriptional regulators ubiquitously expressed in mamma...
Modulation FOXO transcription factor activities can lead to a variety of cellular outputs resulting ...
Phosphorylation of FOXO transcription factors is one of the key mechanisms involved in the regulatio...
Under a Creative Commons license.Transcription factors of the forkhead box, class O (FoxO) family ar...
Post-Translational Modifications (PTMs) may occur at any stage following the translation process in ...
FoxO3 is a member of the forkhead class of transcription factors and plays a major role in the regul...
FOXO transcription factors are involved in a variety of biological processes including cell cycle re...