Add to ORKGAge-related cognitive decline is a serious health concern in our aging society. Decreased cognitive function ob-served during healthy brain aging is most likely caused by changes in brain connectivity and synaptic dysfunction in particular brain regions. Here we show that aged C57BL/ 6J wild-type mice have hippocampus-dependent spatial memory impairments. To identify the molecular mecha-nisms that are relevant to these memory deficits, we in-vestigated the temporal profile of mouse hippocampa
Aging is associated with a general decline in cognitive functions, which appears to be due to altera...
International audienceEpisodic memory decline is one of the earlier deficits occurring during normal...
The hippocampus plays a crucial role in the formation of spatial memories, and it is thought that ad...
Age-related cognitive decline is a serious health concern in our aging society. Decreased cognitive ...
Age-related cognitive decline is a serious health concern in our aging society. Decreased cognitive ...
We have carried out a global survey of age-related changes in mRNA levels in the C57BL/6NIA mouse hi...
During the last decades, most of the preclinical neurodegenerative research was performed in mouse m...
Even in the absence of neurodegenerative diseases, progressing age often coincides with cognitive de...
Even in the absence of neurodegenerative diseases, progressing age often coincides with cognitive de...
As the human life span increases, the number of people suffering from cognitive decline is rising dr...
Cognitive decline is one of the earliest hallmarks of both normal and pathological brain aging. Here...
Cognitive decline is one of the earliest hallmarks of both normal and pathological brain aging. Here...
Aging is a prominent risk factor for cognitive decline and neurodegenerative disease. Particularly s...
Cognitive decline is one of the earliest hallmarks of both normal and pathological brain aging. Here...
Spatial memory declines in normal aging while the decline manifests much more severely during aging ...
Aging is associated with a general decline in cognitive functions, which appears to be due to altera...
International audienceEpisodic memory decline is one of the earlier deficits occurring during normal...
The hippocampus plays a crucial role in the formation of spatial memories, and it is thought that ad...
Age-related cognitive decline is a serious health concern in our aging society. Decreased cognitive ...
Age-related cognitive decline is a serious health concern in our aging society. Decreased cognitive ...
We have carried out a global survey of age-related changes in mRNA levels in the C57BL/6NIA mouse hi...
During the last decades, most of the preclinical neurodegenerative research was performed in mouse m...
Even in the absence of neurodegenerative diseases, progressing age often coincides with cognitive de...
Even in the absence of neurodegenerative diseases, progressing age often coincides with cognitive de...
As the human life span increases, the number of people suffering from cognitive decline is rising dr...
Cognitive decline is one of the earliest hallmarks of both normal and pathological brain aging. Here...
Cognitive decline is one of the earliest hallmarks of both normal and pathological brain aging. Here...
Aging is a prominent risk factor for cognitive decline and neurodegenerative disease. Particularly s...
Cognitive decline is one of the earliest hallmarks of both normal and pathological brain aging. Here...
Spatial memory declines in normal aging while the decline manifests much more severely during aging ...
Aging is associated with a general decline in cognitive functions, which appears to be due to altera...
International audienceEpisodic memory decline is one of the earlier deficits occurring during normal...
The hippocampus plays a crucial role in the formation of spatial memories, and it is thought that ad...