Polymeric IgA myeloma, hyperlipidaemia and xanthomatosis: a further case and review

A patient is described who had myeloma of the polymeric IgA variety, together with a striking hyper-lipidaemia and xanthomatosis. Investigations into the protein and lipid abnormality failed to demon-strate any mechanism for the hyperlipidaemia. A re-view of the literature, however, validates this clinical entity and some of the suggested explanations are discussed