Add to ORKGBackground Germline mutations in the PALB2 gene have been implicated in both breast cancer and pancreatic cancer susceptibility. The extent to which PALB2 mutations account for cancer susceptibility in breastepancreas cancer families is unknown. Methods High Resolution Melting analysis and Multiplex Ligation-dependent Probe Amplification were performed to investigate the prevalence of PALB2 mutations in patients with either a personal history of both breast and pancreatic cancer or a personal history of breast cancer and a family history of a first degree relative with pancreatic cancer. Results No PALB2 mutations were identified in 77 breastepancreas cancer families, which included 22 probands with a personal history of both breast and pan...
Pancreatic adenocarcinoma (PC) is the third most common cancer associated with BRCA mutations. Most ...
BACKGROUND : Germline loss-of-function mutations in PALB2 are known to confer a predisposition to br...
BACKGROUND : Germline loss-of-function mutations in PALB2 are known to confer a predisposition to br...
textabstractPALB2-mutation carriers not only have an increased risk for breast cancer (BC) but also ...
PALB2-mutation carriers not only have an increased risk for breast cancer (BC) but also for pancreat...
PALB2-mutation carriers not only have an increased risk for breast cancer (BC) but also for pancreat...
PALB2-mutation carriers not only have an increased risk for breast cancer (BC) but also for pancreat...
PALB2-mutation carriers not only have an increased risk for breast cancer (BC) but also for pancreat...
Abstract Background PALB2 has emer...
PALB2 gene is mutated in about 1–2 % of familial breast cancer as well as in 3–4 % of familial pancr...
<div><p>Background</p><p>The <i>PALB2</i> gene, also known as <i>FANCN</i>, forms a bond and co-loca...
Pancreatic adenocarcinoma (PC) is the third most common cancer associated with BRCA mutations. Most ...
Pancreatic adenocarcinoma (PC) is the third most common cancer associated with BRCA mutations. Most ...
Partner and localiser of BRCA2 forms part of a macromolecular complex with BRCA1 and BRCA2, which is...
NTRODUCTION: As a group, women who carry germline mutations in partner and localizer of breast cance...
Pancreatic adenocarcinoma (PC) is the third most common cancer associated with BRCA mutations. Most ...
BACKGROUND : Germline loss-of-function mutations in PALB2 are known to confer a predisposition to br...
BACKGROUND : Germline loss-of-function mutations in PALB2 are known to confer a predisposition to br...
textabstractPALB2-mutation carriers not only have an increased risk for breast cancer (BC) but also ...
PALB2-mutation carriers not only have an increased risk for breast cancer (BC) but also for pancreat...
PALB2-mutation carriers not only have an increased risk for breast cancer (BC) but also for pancreat...
PALB2-mutation carriers not only have an increased risk for breast cancer (BC) but also for pancreat...
PALB2-mutation carriers not only have an increased risk for breast cancer (BC) but also for pancreat...
Abstract Background PALB2 has emer...
PALB2 gene is mutated in about 1–2 % of familial breast cancer as well as in 3–4 % of familial pancr...
<div><p>Background</p><p>The <i>PALB2</i> gene, also known as <i>FANCN</i>, forms a bond and co-loca...
Pancreatic adenocarcinoma (PC) is the third most common cancer associated with BRCA mutations. Most ...
Pancreatic adenocarcinoma (PC) is the third most common cancer associated with BRCA mutations. Most ...
Partner and localiser of BRCA2 forms part of a macromolecular complex with BRCA1 and BRCA2, which is...
NTRODUCTION: As a group, women who carry germline mutations in partner and localizer of breast cance...
Pancreatic adenocarcinoma (PC) is the third most common cancer associated with BRCA mutations. Most ...
BACKGROUND : Germline loss-of-function mutations in PALB2 are known to confer a predisposition to br...
BACKGROUND : Germline loss-of-function mutations in PALB2 are known to confer a predisposition to br...