Oral manifestations of acute promyelocytic leukemia: A case report

Acute leukemia is often associated with oral manifes-tations. We report an acute promyelocytic leukemia (APL) case with oral manifestations leading to the diagnosis. A 21-year-old female visited our hospital with complaints of gingival bleeding and swelling of the left lower wisdom tooth. The patient’s complete blood count revealed a marked increase in white blood cells and a decrease in red blood cells and an abnormal leukocyte differential, and APL was diag-nosed on the basis of bone marrow samples in the in-ternal medicine department. The patient was treated with all-trans-retinoic acid combined with chemo-therapy and has maintained clinical and molecular complete remission at 12 months of follow-up. Dental professionals should be aware of clinical manifesta-tions and complications associated with these malign-nant neoplastic diseases to aid in diagnosis and sub-sequent treatment and management