liquid media

In the light of current interest in Neisseria gonorrhoeae, attempts have recently been made to develop a growth medium which would permit production of the organisms in bulk. In these studies it was important to ensure that stability of colonial types was maintained during growth. Kellogg, Peacock, Deacon, Brown, and Pirkle (1963) observed that the gonococcus underwent morphological variation in which four colonial types were observed. These are Types 1 and 2, virulent for man and for fertile hens ' eggs, and relatively avirulent Types 3 and 4. Since that time, Jephcott and Reyn (1971) have detected another colonial type, which they hav