Both of these methods, balloon as well as

GDC, have been frequently used also for em-bolization of parent vessels. As a result, an ac-cumulation of experience resulted in their broad applicability. Recently, in Europe and United State, endovascular approach have be-come the method of first choice for manage-ment of intracranial aneurysms, and is also in-creasing in the other world. In our country, the number of institutions us-ing this approach is rising, though neck clipping still remains a method of the first choice. Our indication of endovascular approach de-pends on the localization of lesion: aneurysms in the cavernous internal carotid artery, top of the basilar artery and dissection of the verte-bral artery are treated by coiling; aneurysms of ICPC, Acom and VA-PICA aneurysms are treated by clipping or coil. Finally, MCA, AC distal and the other aneurysms are treated mainly by clipping. In addition individual pa-tient’s conditions, such as advanced age, heart disease, serious subarachnoid hemorrhage and others, which should be carefully examined play a crucial role in choosing of appropriate method before making decision about therapy indications. Here are some drawbacks of balloon and Summary Recently, endovascular surgery became com-mon approach for management of intracranial aneurysms. Though its efficacy, this approach is still new and under development. Here, we re-port our clinical experience in patients treated with two methods – balloon or Gugliemi detach-able coil. In addition, to understand better the mecha-nisms underlying postoperative complications, we studied them in histopathological specimens of patients and in a model of experimental aneurysm. From our data we conclude that choice of appropriate therapeutic method should respect specific conditions of patients as well as of facility. Careful postoperative studies including exam-ination of intravascular surface by endovascular scope examination would be useful for predic-tion of possible complications