Sertoli cells are the epithelial cells responsible for the onset of pubertal development and the maintenance of spermatogen-esis in the adult. Transferrin is one of the major secretory prod-ucts expressed by differentiated Sertoli cells. Investigation of the transcriptional control of transferrin gene expression provides insight regarding the regulation of Sertoli cell differentiation. The optimal activation of the mouse transferrin promoter (mTf) by FSH requires the synergistic actions of the cAMP response element-binding protein (CREB) binding to the cAMP response element-like proximal region II (PRII) and the basic helix-loop-helix (bHLH) binding to the E-box. Proximal region II alone is sufficient for cAMP-mediated activation. The proxi...
The proliferation and differentiation of Sertoli cells is regulated by follicle-stimulating hormone ...
We have recently shown that phospho-cAMP response element-binding protein (CREB) is essential but no...
AbstractPrimordial germ cells (PGCs) are the embryonic precursors of the adult gametes. Although res...
One of the primary endocrine hormones that influence the onset of Sertoli cell differentiation at pu...
One of the primary endocrine hormones that influence the onset of Sertoli cell differentiation at pu...
The action of follicle-stimulating hormone (FSH) in spermatogenesis is regulated at a fundame...
Background and aim: Basic fibroblast growth factor (bFGF) and interleukin 1β (IL1β) belong to the se...
All in-text references underlined in blue are linked to publications on ResearchGate, letting you ac...
Nectin-2, a major protein component of the adherens junctions (AJs), is found between Sertoli cells ...
cAMP response element binding protein (CREB)-binding protein (CBP) and p300 are two structurally rel...
ABSTRACT cAMP response element binding protein (CREB)-binding protein (CBP) and p300 are two structu...
The transcriptional transactivational activities of the phosphoprotein cAMP-response element-binding...
The differentiation of male germ cell requires spermatogenic stage and cell-specific gene expression...
Transcription factors members of the basic leucine zipper (bZIP) class play important roles in the r...
The proliferation and differentiation of Sertoli cells is regulated by follicle-stimulating hormone ...
The proliferation and differentiation of Sertoli cells is regulated by follicle-stimulating hormone ...
We have recently shown that phospho-cAMP response element-binding protein (CREB) is essential but no...
AbstractPrimordial germ cells (PGCs) are the embryonic precursors of the adult gametes. Although res...
One of the primary endocrine hormones that influence the onset of Sertoli cell differentiation at pu...
One of the primary endocrine hormones that influence the onset of Sertoli cell differentiation at pu...
The action of follicle-stimulating hormone (FSH) in spermatogenesis is regulated at a fundame...
Background and aim: Basic fibroblast growth factor (bFGF) and interleukin 1β (IL1β) belong to the se...
All in-text references underlined in blue are linked to publications on ResearchGate, letting you ac...
Nectin-2, a major protein component of the adherens junctions (AJs), is found between Sertoli cells ...
cAMP response element binding protein (CREB)-binding protein (CBP) and p300 are two structurally rel...
ABSTRACT cAMP response element binding protein (CREB)-binding protein (CBP) and p300 are two structu...
The transcriptional transactivational activities of the phosphoprotein cAMP-response element-binding...
The differentiation of male germ cell requires spermatogenic stage and cell-specific gene expression...
Transcription factors members of the basic leucine zipper (bZIP) class play important roles in the r...
The proliferation and differentiation of Sertoli cells is regulated by follicle-stimulating hormone ...
The proliferation and differentiation of Sertoli cells is regulated by follicle-stimulating hormone ...
We have recently shown that phospho-cAMP response element-binding protein (CREB) is essential but no...
AbstractPrimordial germ cells (PGCs) are the embryonic precursors of the adult gametes. Although res...