Insulin Sensitivity and Associated Risk Factors in Mexican Children and Adolescents

There is an increasing amount of datashowing that being overweight dur-ing childhood and adolescence is significantly associated with insulin resis-tance in young adulthood. Weight loss in obese youngsters results in a decrease in insulin concentration and improvement in insulin sensitivity (1). The objective of this study was to identify the principal risk factors associated with insulin sensi-tivity in a group of Mexican children and adolescents with a wide range of body weight. RESEARCH DESIGN AND METHODS — One hundred male and female children and youth subjects aged between 10 and 20 years, from differen