Background: A diet high in red meat is an established colorectal cancer (CRC) risk factor. Carcinogens generated during meat cooking have been implicated as causal agents and can induce oxidative DNA damage, which elicits repair by the base excision repair (BER) pathway. Methods: Using a family-based study, we investigated the role of polymorphisms in 4 BER genes (APEX1 Gln51His, Asp148Glu;OGG1 Ser236Cys; PARPVal742Ala; andXRCC1Arg194Trp, Arg280His, Arg399Gln) as potential CRC risk factors andmodifiers of the association between diets high in redmeat or poultry and CRC risk. We tested for gene–environment interactions using case-only analyses (n 577) and compared statistically significant results with those obtained using case-unaffected s...
Contains fulltext : 59301.pdf (publisher's version ) (Closed access)OBJECTIVE: We ...
BACKGROUND: Red meat intake has been associated with risk of colorectal cancer, potentially mediated...
Abstract: Red meat is a risk factor for colorectal cancer (CRC). We wanted to evaluate whether a fun...
A diet high in red meat is an established colorectal cancer (CRC) risk factor. Carcinogens generated...
Heterocyclic aromatic amines formed in cooked meat may be an underlying mechanism for the red meat-c...
Background: Red meat intake has been associated with risk of colorectal cancer, potentially mediated...
UnrestrictedRed meat intake has been associated with colorectal cancer (CRC) risk with some consiste...
Much of the DNA damage from colon cancer-related carcinogens, including heterocyclic amines (HCA) an...
Diets high in red meat have been consistently associated with colorectal cancer (CRC) risk and may r...
Diets high in red meat are established risk factors for colorectal cancer (CRC). Carcinogenic compou...
Introduction: Meat consumption is a risk factor for colorectal cancer. This research investigated th...
Dietary factors, including meat, fruits, vegetables and fiber, are associated with colorectal cancer...
With the advent of human genome sequencing project, came the wave of personalized genomics. Scientis...
Polymorphisms in base excision repair genes as colorectal cancer risk factors and modifiers of the e...
Thesis (Ph.D.)--University of Washington, 2020Colorectal cancer (CRC) is the second most commonly di...
Contains fulltext : 59301.pdf (publisher's version ) (Closed access)OBJECTIVE: We ...
BACKGROUND: Red meat intake has been associated with risk of colorectal cancer, potentially mediated...
Abstract: Red meat is a risk factor for colorectal cancer (CRC). We wanted to evaluate whether a fun...
A diet high in red meat is an established colorectal cancer (CRC) risk factor. Carcinogens generated...
Heterocyclic aromatic amines formed in cooked meat may be an underlying mechanism for the red meat-c...
Background: Red meat intake has been associated with risk of colorectal cancer, potentially mediated...
UnrestrictedRed meat intake has been associated with colorectal cancer (CRC) risk with some consiste...
Much of the DNA damage from colon cancer-related carcinogens, including heterocyclic amines (HCA) an...
Diets high in red meat have been consistently associated with colorectal cancer (CRC) risk and may r...
Diets high in red meat are established risk factors for colorectal cancer (CRC). Carcinogenic compou...
Introduction: Meat consumption is a risk factor for colorectal cancer. This research investigated th...
Dietary factors, including meat, fruits, vegetables and fiber, are associated with colorectal cancer...
With the advent of human genome sequencing project, came the wave of personalized genomics. Scientis...
Polymorphisms in base excision repair genes as colorectal cancer risk factors and modifiers of the e...
Thesis (Ph.D.)--University of Washington, 2020Colorectal cancer (CRC) is the second most commonly di...
Contains fulltext : 59301.pdf (publisher's version ) (Closed access)OBJECTIVE: We ...
BACKGROUND: Red meat intake has been associated with risk of colorectal cancer, potentially mediated...
Abstract: Red meat is a risk factor for colorectal cancer (CRC). We wanted to evaluate whether a fun...