Add to ORKGcalled filopodia, often establish adhesive contacts with the cellular surroundings with a subsequent build up of retraction force. This process seems to be impor-tant for cell migration, embryonic devel-opment, wound healing, and pathogenic infection pathways. We have shown that filopodial tips are able to sense adhesive contact and, as a consequence, locally reduce actin polymerization speed. This induces filopodial retraction via forces generated by the cell membrane ten-sion and by the filopodial actin shaft that is constantly pulled rearwards via the retrograde flow of actin at the base
This review discusses recent advances in our understanding of the role filopodia and filopodia-like ...
<p><b>A.</b> Scatter plot of the part of the contact time of a filopodia adhesion with the advancing...
Background: Cells use filopodia to explore their environment and to form new adhesion contacts for m...
The ability of mammalian cells to adhere and to migrate is an essential prerequisite to form higher ...
<div><p>While cell-substrate adhesions that form between the protruding edge of a spreading cell and...
Numerous F-actin containing structures are involved in regulating protrusion of membrane at the lead...
While cell-substrate adhesions that form between the protruding edge of a spreading cell and flat su...
Filopodia are dynamic, actin-rich fin-ger-like structures that protrude from the cell membrane and p...
Filopodia are dynamic, narrow, plasma membrane protrusions filled with bundled actin filaments. Fres...
Filopodia protrude from the leading edge of cells and play important roles in cell motility. Here we...
Filopodia are thin, actin-rich plasma-membrane protrusions that function as antennae for cells to pr...
in filopodia tips, predicts critical roles for PIs in regulating filopodia ultra-structure and funct...
Filopodia are finger-like protrusions from the plasma membrane and are of fundamental importance to ...
Migration of cells is one of the most essential prerequisites to form higher organisms and depends o...
<p><b>A.</b> Time-lapse montage of the cell edge region containing a disassembling filopodia adhesio...
This review discusses recent advances in our understanding of the role filopodia and filopodia-like ...
<p><b>A.</b> Scatter plot of the part of the contact time of a filopodia adhesion with the advancing...
Background: Cells use filopodia to explore their environment and to form new adhesion contacts for m...
The ability of mammalian cells to adhere and to migrate is an essential prerequisite to form higher ...
<div><p>While cell-substrate adhesions that form between the protruding edge of a spreading cell and...
Numerous F-actin containing structures are involved in regulating protrusion of membrane at the lead...
While cell-substrate adhesions that form between the protruding edge of a spreading cell and flat su...
Filopodia are dynamic, actin-rich fin-ger-like structures that protrude from the cell membrane and p...
Filopodia are dynamic, narrow, plasma membrane protrusions filled with bundled actin filaments. Fres...
Filopodia protrude from the leading edge of cells and play important roles in cell motility. Here we...
Filopodia are thin, actin-rich plasma-membrane protrusions that function as antennae for cells to pr...
in filopodia tips, predicts critical roles for PIs in regulating filopodia ultra-structure and funct...
Filopodia are finger-like protrusions from the plasma membrane and are of fundamental importance to ...
Migration of cells is one of the most essential prerequisites to form higher organisms and depends o...
<p><b>A.</b> Time-lapse montage of the cell edge region containing a disassembling filopodia adhesio...
This review discusses recent advances in our understanding of the role filopodia and filopodia-like ...
<p><b>A.</b> Scatter plot of the part of the contact time of a filopodia adhesion with the advancing...
Background: Cells use filopodia to explore their environment and to form new adhesion contacts for m...