Background. Estimates for the annual progression rate from Barrett’s esophagus (BE) to esophageal adenocarcinoma (EAC) vary widely. In this explorative study, we quantified how this uncertainty affects the estimates of effectiveness and efficiency of screening and treatment for EAC. Design. We developed 3 versions of the University of Washington / Microsimulation Screening Analysis–EAC model. The mod-els differed with respect to the annual progression rate from BE to EAC (0.12 % or 0.42%) and the possibility of spontane-ous regression of dysplasia (yes or no). All versions of the model were calibrated to the observed Surveillance, Epide-miology, and End Results esophageal cancer incidence rates from 1998 to 2009. To identify the impact of n...
The incidence of esophageal adenocarcinoma (EAC) has risen rapidly in the U.S. and western world. Th...
Background: The incidence of esophageal adenocarcinoma (EAC) has increased five-fold in the United S...
Background: Endoscopic surveillance of Barrett’s esophagus (BE) is probably not cost-effective. A su...
Background. Estimates for the annual progression rate from Barrett's esophagus (BE) to esophageal ad...
Background & Aims Published estimates for the rate of progression from Barrett's esophagus (BE) to e...
Background Individuals with Barrett’s esophagus (BE) are at increased risk of high-grade dysplasia (...
Esophageal adenocarcinoma has poor 5-year survival rates. Increased survivalmight be achieved with e...
Background: Current surveillance guidelines for identifying patients with Barrett’s esophagus (BE) a...
BACKGROUND & AIMS: A system is needed to determine the risk of patients with Barrett\u27s esophagus ...
Background: Esophageal adenocarcinoma is a disease that has a high mortality rate, the only known pr...
Esophageal adenocarcinoma (EAC) is the most common type of esophageal cancer in Western countries. V...
Background & Aims: Esophageal adenocarcinoma (EAC) develops rapidly and has a high mortality rate. W...
Objectives: The current surveillance strategy in Barrett's esophagus (BE) uses only histological fin...
Barrett's esophagus (BE) is the only known precursor to esophageal adenocarcinoma (EAC), whose incid...
Barrett's esophagus predisposes to esophageal adenocarcinoma. However, the value of endoscopic surve...
The incidence of esophageal adenocarcinoma (EAC) has risen rapidly in the U.S. and western world. Th...
Background: The incidence of esophageal adenocarcinoma (EAC) has increased five-fold in the United S...
Background: Endoscopic surveillance of Barrett’s esophagus (BE) is probably not cost-effective. A su...
Background. Estimates for the annual progression rate from Barrett's esophagus (BE) to esophageal ad...
Background & Aims Published estimates for the rate of progression from Barrett's esophagus (BE) to e...
Background Individuals with Barrett’s esophagus (BE) are at increased risk of high-grade dysplasia (...
Esophageal adenocarcinoma has poor 5-year survival rates. Increased survivalmight be achieved with e...
Background: Current surveillance guidelines for identifying patients with Barrett’s esophagus (BE) a...
BACKGROUND & AIMS: A system is needed to determine the risk of patients with Barrett\u27s esophagus ...
Background: Esophageal adenocarcinoma is a disease that has a high mortality rate, the only known pr...
Esophageal adenocarcinoma (EAC) is the most common type of esophageal cancer in Western countries. V...
Background & Aims: Esophageal adenocarcinoma (EAC) develops rapidly and has a high mortality rate. W...
Objectives: The current surveillance strategy in Barrett's esophagus (BE) uses only histological fin...
Barrett's esophagus (BE) is the only known precursor to esophageal adenocarcinoma (EAC), whose incid...
Barrett's esophagus predisposes to esophageal adenocarcinoma. However, the value of endoscopic surve...
The incidence of esophageal adenocarcinoma (EAC) has risen rapidly in the U.S. and western world. Th...
Background: The incidence of esophageal adenocarcinoma (EAC) has increased five-fold in the United S...
Background: Endoscopic surveillance of Barrett’s esophagus (BE) is probably not cost-effective. A su...