Neuroblastoma is an extra-cranial solid tumor of the nervous system occurring predominantly in infants and children younger than five years of age. Neuroblastoma presents a challenge to therapy primarily due to a decreased responsiveness to anti-cancer agents like cisplatin (CDDP), leading to recurrence. Vitamin A and its derivatives, known as retinoids, are preventive against cancer and induce differentiation in some cell lines. Retinoids are now being tested clinically for the treatment of neuroblastoma. One major limitation to retinoid therapy is the development of chemoresistance. In the present study human SK-N-SH neuroblastoma cells pretreate
SIGLEAvailable from British Library Document Supply Centre-DSC:DXN019080 / BLDSC - British Library D...
none8noRetinoids are lipophilic compounds derived from vitamin A, which have been extensively studie...
Neuroblastoma (NB), originating from neural crest cells, is the most common extracranial tumor of ch...
Retinoids are analogues of vitamin A, with documented activity against various malignant cell types....
A neuroblastoma (NB) is a solid paediatric tumour arising from undifferentiated neuronal cells. Desp...
The molecular mechanisms of neuroblastoma tumorigenesis include arrested neuritic differentiation, m...
A variety of pre-clinical and clinical data point toward high drug levels of retinoids being require...
Neuroblastoma (NB) is the most common extracranial solid childhood tumor accounting for around 15% o...
Cancer is a well-known disease that many people encounter in their lifetime. There is constantly res...
Objective : Neuroblastoma is one of common childhood tumors. Although its mortality is very high, th...
Restricted until 14 Apr. 2011.Neuroblastoma is a childhood neuroendocrine tumor, which originates fr...
dissertationNeuroblastoma is the most common extracranial solid tumor in children. Despite increases...
Aim: Neuroblastoma is an important pediatric tumor in which Myc-N amplification is a well-known poor...
BACKGROUND:Neuroblastma cell lines contain a side-population of cells which express stemness markers...
Neuroblastoma, a malignant neoplasm that arises in the adre-nal medulla or sympathetic ganglion, is ...
SIGLEAvailable from British Library Document Supply Centre-DSC:DXN019080 / BLDSC - British Library D...
none8noRetinoids are lipophilic compounds derived from vitamin A, which have been extensively studie...
Neuroblastoma (NB), originating from neural crest cells, is the most common extracranial tumor of ch...
Retinoids are analogues of vitamin A, with documented activity against various malignant cell types....
A neuroblastoma (NB) is a solid paediatric tumour arising from undifferentiated neuronal cells. Desp...
The molecular mechanisms of neuroblastoma tumorigenesis include arrested neuritic differentiation, m...
A variety of pre-clinical and clinical data point toward high drug levels of retinoids being require...
Neuroblastoma (NB) is the most common extracranial solid childhood tumor accounting for around 15% o...
Cancer is a well-known disease that many people encounter in their lifetime. There is constantly res...
Objective : Neuroblastoma is one of common childhood tumors. Although its mortality is very high, th...
Restricted until 14 Apr. 2011.Neuroblastoma is a childhood neuroendocrine tumor, which originates fr...
dissertationNeuroblastoma is the most common extracranial solid tumor in children. Despite increases...
Aim: Neuroblastoma is an important pediatric tumor in which Myc-N amplification is a well-known poor...
BACKGROUND:Neuroblastma cell lines contain a side-population of cells which express stemness markers...
Neuroblastoma, a malignant neoplasm that arises in the adre-nal medulla or sympathetic ganglion, is ...
SIGLEAvailable from British Library Document Supply Centre-DSC:DXN019080 / BLDSC - British Library D...
none8noRetinoids are lipophilic compounds derived from vitamin A, which have been extensively studie...
Neuroblastoma (NB), originating from neural crest cells, is the most common extracranial tumor of ch...