Copyright © 1991, American Society for Microbiology Detection and Titration of Measles Virus Antibody by Hemagglutination Inhibition and by

Measles continues to be a major disease of both human and nonhuman primates. The dot immunobinding assay, a modified enzyme immunoassay, permits the detection of measles virus antibody in the nonlaboratory setting with either serum or whole blood collected on filter paper. Measles is a significant disease of both human and nonhu-man primates. Since the introduction of human vaccine programs, the incidence of measles in humans has sharply decreased. Outbreaks continue to occur, however, and the determination of the presence or absence of antibody con-tinues to be the method of choice for detection of immunity. Measles is also an important disease in nonhuman primates, particularly among young animals. Species variation in sus-ceptibility to measles virus infection is recognized. Subclin-ical infection is the most common manifestation, but fatali-ties do occur, particularly in New World species. Monkeys in the wild apparently are free of measles, contractin