Add to ORKG(Received for publication October 17,1966) Gout has been recognized as a famil-ial disorder since Galen (1) (A.D. 131— 201) ascribed the origin of the disease to "debauchery, intemperance and a hereditary trait". Since that time many investigators have substantiated the finding of familial aggregation of hy-peruricemia and gout, but conflicting theories have been proposed concerning the mode of inheritance of these traits. In 1948 Smyth et al. (2) studied 87 relatives of 19 gouty male patients and concluded that hyperuricemia and gout 1From the Departments of Epidemiology and Biostatistics, School of Public Health an
No Abstract.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/37701/1/1780080450_ftp.pd
It had long been suspected that gout might be a disease of varying origins, but it has only been dur...
biochemical function other than being an end product of purine metabolism, was first discovered in 1...
Though the hereditary nature of gouty arthritis has been recognized for centuries, systematic studie...
THERE is now some indication that the clinical syndrome of gout may well comprise several distinct a...
Medical interest in the etiology of gout has bidden fair to outlive the disease itself. It is just p...
SUMMARY Clinical gout and renal failure was seen in a 9-year-old girl. The family tree showed that 9...
A B STRA C T The plasma levels of the urate-binding a1-a2-globulin, as determined by its urate-bindi...
It is generally agreed that hyperuricaemia is inherited, although the exact mechanism of in-heritanc...
OBJECTIVE: To examine familial aggregation of gout and to estimate the heritability and environmenta...
In an editorial that appeared elsewhere in I 960 23, the author ventured some speculations as to the...
Although a genetic predisposition to gout has been recognised for centuries, its mechanism has never...
OBJECTIVES: Throughout history, gout has been referred to as the "disease of the kings", and has ...
Gout is a common rheumatic disease in humans which is characterized by elevation in serum uric acid ...
[[abstract]]Objective. The prevalence of gout and hyperuricemia in Taiwanese aborigines is remarkabl...
No Abstract.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/37701/1/1780080450_ftp.pd
It had long been suspected that gout might be a disease of varying origins, but it has only been dur...
biochemical function other than being an end product of purine metabolism, was first discovered in 1...
Though the hereditary nature of gouty arthritis has been recognized for centuries, systematic studie...
THERE is now some indication that the clinical syndrome of gout may well comprise several distinct a...
Medical interest in the etiology of gout has bidden fair to outlive the disease itself. It is just p...
SUMMARY Clinical gout and renal failure was seen in a 9-year-old girl. The family tree showed that 9...
A B STRA C T The plasma levels of the urate-binding a1-a2-globulin, as determined by its urate-bindi...
It is generally agreed that hyperuricaemia is inherited, although the exact mechanism of in-heritanc...
OBJECTIVE: To examine familial aggregation of gout and to estimate the heritability and environmenta...
In an editorial that appeared elsewhere in I 960 23, the author ventured some speculations as to the...
Although a genetic predisposition to gout has been recognised for centuries, its mechanism has never...
OBJECTIVES: Throughout history, gout has been referred to as the "disease of the kings", and has ...
Gout is a common rheumatic disease in humans which is characterized by elevation in serum uric acid ...
[[abstract]]Objective. The prevalence of gout and hyperuricemia in Taiwanese aborigines is remarkabl...
No Abstract.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/37701/1/1780080450_ftp.pd
It had long been suspected that gout might be a disease of varying origins, but it has only been dur...
biochemical function other than being an end product of purine metabolism, was first discovered in 1...