Add to ORKGFunctional RNA structures tend to be conserved during evolution. This finding is, for example, ex-ploited by comparative methods for RNA secondary structure prediction that currently provide the state-of-art in terms of prediction accuracy. We here provide strong evidence that homologous RNA genes not only fold into similar final RNA structures, but that their folding pathways also share common transient structural features that have been evolu-tionarily conserved. For this, we compile and inves-tigate a non-redundant data set of 32 sequences with known transient and final RNA secondary structures and devise a dedicated computational analysis pipeline
Thesis (Ph.D.)--University of Rochester. School of Medicine & Dentistry. Dept. of Biochemistry and B...
In the realm of nucleic acid structures, secondary structure forms a conceptually important intermed...
In recent years it has become evident that functional RNAs in living organisms are not just curious ...
Functional RNA structures tend to be conserved during evolution. This finding is, for example, ex-pl...
Functional RNA structures tend to be conserved during evolution. This finding is, for example, ex-pl...
Functional RNA structures tend to be conserved during evolution. This finding is, for example, explo...
State-of-the-art methods in RNA secondary structure prediction focus on predicting the final, functi...
State-of-the-art methods in RNA secondary structure prediction focus on predicting the final, functi...
In recent years it has become evident that functional RNAs in living organisms are not just curious ...
In recent years it has become evident that functional RNAs in living organisms are not just curious ...
Abstract In recent years it has become evident that functional RNAs in living organisms are not just...
Existing computational methods for RNA secondary-structure prediction tacitly assume RNA to only enc...
RNA not only codes protein sequences, it also functions by having specific structures. Because RNA s...
Existing computational methods for RNA secondary-structure prediction tacitly assume RNA to only enc...
The prediction of functional RNA structures has attracted increased interest, as it allows us to stu...
Thesis (Ph.D.)--University of Rochester. School of Medicine & Dentistry. Dept. of Biochemistry and B...
In the realm of nucleic acid structures, secondary structure forms a conceptually important intermed...
In recent years it has become evident that functional RNAs in living organisms are not just curious ...
Functional RNA structures tend to be conserved during evolution. This finding is, for example, ex-pl...
Functional RNA structures tend to be conserved during evolution. This finding is, for example, ex-pl...
Functional RNA structures tend to be conserved during evolution. This finding is, for example, explo...
State-of-the-art methods in RNA secondary structure prediction focus on predicting the final, functi...
State-of-the-art methods in RNA secondary structure prediction focus on predicting the final, functi...
In recent years it has become evident that functional RNAs in living organisms are not just curious ...
In recent years it has become evident that functional RNAs in living organisms are not just curious ...
Abstract In recent years it has become evident that functional RNAs in living organisms are not just...
Existing computational methods for RNA secondary-structure prediction tacitly assume RNA to only enc...
RNA not only codes protein sequences, it also functions by having specific structures. Because RNA s...
Existing computational methods for RNA secondary-structure prediction tacitly assume RNA to only enc...
The prediction of functional RNA structures has attracted increased interest, as it allows us to stu...
Thesis (Ph.D.)--University of Rochester. School of Medicine & Dentistry. Dept. of Biochemistry and B...
In the realm of nucleic acid structures, secondary structure forms a conceptually important intermed...
In recent years it has become evident that functional RNAs in living organisms are not just curious ...